EGFR-IN-53

• 常用名: EGFR-IN-53
• 英文名: EGFR-IN-53
• CAS号: 2418549-33-2
• 分子量: 287.34
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₁₃N₃O₂S
• 熔点: N/A
• 闪点: N/A

EGFR-IN-53用途

EGFR-IN-53(化合物7)是一种有效的EGFR抑制剂,IC50为8.264µM。EGFR-IN-53对癌细胞系具有细胞毒活性【1】。

EGFR-IN-53名称

• 英文名: EGFR-IN-53

EGFR-IN-53生物活性

• 描述: EGFR-IN-53(化合物7)是一种有效的EGFR抑制剂,IC50为8.264µM。EGFR-IN-53对癌细胞系具有细胞毒活性【1】。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> JAK/STAT信号通路 >> EGFR
  信号通路 >> 蛋白酪氨酸激酶 >> EGFR
• 靶点实验:

  EGFR:8.264 μM (IC50)

• 参考文献:

  [1]. Abbas SY, et al. Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study. Eur J Med Chem. 2020 Jul 15;198:112363.

EGFR-IN-53物理化学性质

• 分子式: C₁₄H₁₃N₃O₂S
• 分子量: 287.34

EGFR-IN-53靶点实验

查看更多实验

实验名称：Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability by S... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4769427

实验名称：Cytotoxicity against human WI-38 cells assessed as reduction in cell viability by SRB... 来源：ChEMBL 靶标：WI-38 External Id：CHEMBL4769430

实验名称：Inhibition of EGFR (unknown origin) by FRET assay 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL4769431

实验名称：Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by SRB... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4769428

实验名称：Cytotoxicity against human MCF7 cells assessed as reduction in cell viability by SRB ... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4769429

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