Antifungal agent 53

• 常用名: Antifungal agent 53
• 英文名: Antifungal agent 53
• CAS号: 2422019-76-7
• 分子量: 444.64
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₅Cl₃N₂Se
• 熔点: N/A
• 闪点: N/A

Antifungal agent 53用途

抗真菌剂53(A03)是一种具有抗真菌活性的白色念珠菌CYP51的有效抑制剂。抗真菌剂53防止真菌生物膜的形成。抗真菌剂53也表现出良好的安全性[1]。

Antifungal agent 53名称

• 英文名: Antifungal agent 53

Antifungal agent 53生物活性

• 描述: 抗真菌剂53(A03)是一种具有抗真菌活性的白色念珠菌CYP51的有效抑制剂。抗真菌剂53防止真菌生物膜的形成。抗真菌剂53也表现出良好的安全性[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
• 体外研究: 抗真菌剂53(4μg/mL；24小时)对兔红细胞溶血作用[1] 抗真菌剂53(50μg/mL,80μg/mL；1.5-24小时)呈剂量依赖性抑制白色念珠菌生物膜的形成[1]
• 参考文献:

  [1]. Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360.

Antifungal agent 53物理化学性质

• 分子式: C₁₈H₁₅Cl₃N₂Se
• 分子量: 444.64

Antifungal agent 53靶点实验

查看更多实验

实验名称：Antifungal activity against fluconazole-resistant Candida albicans 17# assessed as in... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4816833

实验名称：Antifungal activity against fluconazole-resistant Candida albicans 632 assessed as in... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4816834

实验名称：Antifungal activity against Aspergillus fumigatus CMGCC3.7795 measured after 72 hrs b... 来源：ChEMBL 靶标：Aspergillus fumigatus External Id：CHEMBL4816831

实验名称：Antifungal activity against fluconazole-resistant Candida albicans CaR assessed as in... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4816832

实验名称：Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incuba... 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL4816837

实验名称：Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability i... 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL4816838

实验名称：Antifungal activity against fluconazole-resistant Candida albicans 901 assessed as in... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4816835

实验名称：Antifungal activity against fluconazole-resistant Candida albicans 904 assessed as in... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4816836

实验名称：Antifungal activity against Candida albicans ATCC SC5314 measured after 24 hrs by bro... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4816825

实验名称：Antifungal activity against Candida zeylanoides CMGCC2.3739 measured after 24 hrs by ... 来源：ChEMBL 靶标：[Candida] zeylanoides External Id：CHEMBL4816826

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