糖精N-(2-乙酸乙酯)(吡罗昔康杂质E)结构式
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常用名 | 糖精N-(2-乙酸乙酯)(吡罗昔康杂质E) | 英文名 | 2-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-6-((TRIMETHYLSILYL)ETHYNYL)FURO[3,2-B]PYRIDINE |
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| CAS号 | 24683-20-3 | 分子量 | 269.27400 | |
| 密度 | 1.442g/cm3 | 沸点 | 441.4ºC at 760 mmHg | |
| 分子式 | C11H11NO5S | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 220.8ºC |
| 中文名 | 2,3-二氢-3-氧代-1,2-苯并异噻唑-2-乙酸乙酯-1,1-二氧化物 |
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| 英文名 | ethyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate |
| 中文别名 | 沙卡林N-(2-醋酸乙酯)(吡罗昔康杂质 E) | 2,3-二氢-3-氧代-1,2-苯异噻唑-2-乙酸乙酯-1,1-二氧化物 |
| 英文别名 | 更多 |
| 密度 | 1.442g/cm3 |
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| 沸点 | 441.4ºC at 760 mmHg |
| 分子式 | C11H11NO5S |
| 分子量 | 269.27400 |
| 闪点 | 220.8ºC |
| 精确质量 | 269.03600 |
| PSA | 89.13000 |
| LogP | 1.41290 |
| InChIKey | YKCQHUPTHHPHGX-UHFFFAOYSA-N |
| SMILES | CCOC(=O)CN1C(=O)c2ccccc2S1(=O)=O |
| 蒸汽压 | 5.45E-08mmHg at 25°C |
| 折射率 | 1.584 |
| 海关编码 | 2934999090 |
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~78%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:CHIESI FARMACEUTICI S.P.A.; ARMANI, Elisabetta; AMARI, Gabriele; CAPALDI, Carmelida; CARZANIGA, Laura; LA PORTA, Elena; GUALA, Matilde Patent: WO2013/57013 A2, 2013 ; Location in patent: Page/Page column 103; 104 ; |
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~89%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:Nikolaev, Vsevolod; Hennig, Lothar; Sieler, Jochim; Rodina, Ludmila; Schulze, Barbel; Nikolaev, Valerij Organic and Biomolecular Chemistry, 2005 , vol. 3, # 22 p. 4108 - 4116 |
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~97%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:Sivaramakrishnan, Santhosh; Cummings, Andrea H.; Gates, Kent S. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 2 p. 444 - 447 |
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~93%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:Nikolaev, Vsevolod; Hennig, Lothar; Sieler, Jochim; Rodina, Ludmila; Schulze, Barbel; Nikolaev, Valerij Organic and Biomolecular Chemistry, 2005 , vol. 3, # 22 p. 4108 - 4116 |
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~87%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:Hu, Yi; Chen, Zhen-Chu; Le, Zhang-Gao; Zheng, Qin-Guo Journal of Chemical Research, 2004 , # 4 p. 276 - 278 |
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~63%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:Da Settimo; Primofiore; La Motta; Simorini; Boldrini; Bianchini Farmaco, 1996 , vol. 51, # 4 p. 261 - 267 |
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~%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 27, # 1-12 p. 109 - 111 |
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~%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 27, # 1-12 p. 109 - 111 |
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~%
糖精N-(2-乙酸乙酯)(吡罗... 24683-20-3 |
| 文献:Chemische Berichte, , vol. 56, p. 1814 |
| 糖精N-(2-乙酸乙酯)(吡罗昔康杂质E)上游产品 8 | |
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| 糖精N-(2-乙酸乙酯)(吡罗昔康杂质E)下游产品 10 | |
| 海关编码 | 2934999090 |
|---|---|
| 中文概述 | 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途 |
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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实验名称:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assay
来源:ChEMBL
靶标:Carbonic anhydrase 12
External Id:CHEMBL3129538
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实验名称:Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydrase assay
来源:ChEMBL
靶标:Carbonic anhydrase 9
External Id:CHEMBL3129539
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实验名称:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay
来源:ChEMBL
靶标:Carbonic anhydrase 1
External Id:CHEMBL3129540
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实验名称:Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:HCMV UL50
External Id:HMS1262
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实验名称:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay
来源:ChEMBL
靶标:Carbonic anhydrase 2
External Id:CHEMBL3129541
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实验名称:Dicer-mediated maturation of pre-microRNA
来源:Center for Chemical Genomics, University of Michigan
靶标:N/A
External Id:TargetID_659_CEMA
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实验名称:Inhibitors of CDC25B-CDK2/CyclinA interaction
来源:Center for Chemical Genomics, University of Michigan
External Id:MScreen:TargetID_600
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实验名称:High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS1303
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实验名称:Cell-based high throughput primary assay to identify activators of GPR151
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id:GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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实验名称:AlphaScreen-based biochemical high throughput primary assay to identify activators of...
来源:The Scripps Research Institute Molecular Screening Center
靶标:N/A
External Id:FBW7_ACT_ALPHA_1536_1X%ACT PRUN
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| Ethyl (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetate |
| ethyl 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl) acetate |
| N-carbethoxymethyl-1,2-benzisothiazole-1,1-dioxide-3-one |
| ethyl (3-oxo-1,2-benzoisothiazol-2(3H)-yl)acetate 1,1-dioxide |
| UNII-KN712V27AV |
| ethyl (1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)acetate |
| Piroxicam Impurity E |
| Piroxicam impurity E [EP] |
| N-(ethoxycarbonyl)methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide |
| Saccharin N-(2-Acetic Acid Ethyl Ester)(Piroxicam Impurity E) |
| 2-<1,1,3-Trioxo-1,2-benzoisothiazol-2(3H)-yl>essigsaeure-ethylester |
| Ethyl 1,2-benzisothiazol-3-one-1,1-dioxide-N-acetate |