Aldose reductase-IN-5

• 常用名: Aldose reductase-IN-5
• 英文名: Aldose reductase-IN-5
• CAS号: 2480090-03-5
• 分子量: 325.32
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₅NO₅
• 熔点: N/A
• 闪点: N/A

Aldose reductase-IN-5用途

作为醛糖还原酶(ALR2)抑制剂,该化合物用于增强抑制兴奋性和抗氧化能力的结合,以延缓糖尿病并发症的进展。

Aldose reductase-IN-5名称

• 英文名: Aldose reductase-IN-5

Aldose reductase-IN-5生物活性

• 描述: 作为醛糖还原酶(ALR2)抑制剂,该化合物用于增强抑制兴奋性和抗氧化能力的结合,以延缓糖尿病并发症的进展。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> 醛糖还原酶
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Chen H,et al. Dihydrobenzoxazinone derivatives as aldose reductase inhibitors with antioxidant activity. Bioorg Med Chem. 2020 Oct 15;28(20):115699.

Aldose reductase-IN-5物理化学性质

• 分子式: C₁₈H₁₅NO₅
• 分子量: 325.32

Aldose reductase-IN-5靶点实验

查看更多实验

实验名称：Selectivity index, ratio of IC50 for rat kidney ALR1 to IC50 for rat lens ALR2 来源：ChEMBL 靶标：N/A External Id：CHEMBL4672510

实验名称：Antioxidant activity assessed as superoxide anion radical scavenging activity incubat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4672513

实验名称：Antioxidant activity assessed as DPPH radical scavenging activity at 100 uM relative ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4672515

实验名称：Antioxidant activity in rat brain homogenate assessed as inhibition of FeCl3/ascorbic... 来源：ChEMBL 靶标：Brain External Id：CHEMBL4672514

实验名称：Antioxidant activity assessed as DPPH radical scavenging activity at 5 uM relative to... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4672517

实验名称：Antioxidant activity assessed as DPPH radical scavenging activity at 10 uM relative t... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4672516

实验名称：Antioxidant activity assessed as DPPH radical scavenging activity at 1 uM relative to... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4672518

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