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5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯

更新时间:2024-01-08 13:32:16

5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯结构式
5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯结构式
品牌特惠专场
常用名 5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯 英文名 ETHYL-5-CHLORO-1,2-DIHYDRO-4-HYDROXY-1-METHYL-2-OXO-3-QUINOLINE CARBOXYLATE
CAS号 248282-10-2 分子量 281.69200
密度 1.436g/cm3 沸点 419ºC at 760mmHg
分子式 C13H12ClNO4 熔点 N/A
MSDS N/A 闪点 207.2ºC

 名称

中文名 5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯
英文名 ethyl 5-chloro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxylate
英文别名 更多

 物理化学性质

密度 1.436g/cm3
沸点 419ºC at 760mmHg
分子式 C13H12ClNO4
分子量 281.69200
闪点 207.2ºC
精确质量 281.04500
PSA 68.53000
LogP 2.07420
蒸汽压 9.03E-08mmHg at 25°C
折射率 1.615

 合成线路

~22%

5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯结构式

5-氯-1,2-二氢-4-羟基...

248282-10-2

文献:Tomassoli, Isabelle; Ismaili, Lhassane; Pudlo, Marc; De Los Rios, Cristobal; Soriano, Elena; Colmena, Ines; Gandia, Luis; Rivas, Luis; Samadi, Abdelouahid; Marco-Contelles, Jose; Refouvelet, Bernard European Journal of Medicinal Chemistry, 2011 , vol. 46, # 1 p. 1 - 10

~73%

5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯结构式

5-氯-1,2-二氢-4-羟基...

248282-10-2

文献:Active Biotech AB Patent: US6133285 A1, 2000 ;

~%

5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯结构式

5-氯-1,2-二氢-4-羟基...

248282-10-2

文献:Active Biotech AB Patent: EP1095021 B1, 2003 ; Location in patent: Page/Page column 6 ;

~%

5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯结构式

5-氯-1,2-二氢-4-羟基...

248282-10-2

文献:Joensson, Stig; Andersson, Gunnar; Fex, Tomas; Fristedt, Tomas; Hedlund, Gunnar; Jansson, Karl; Abramo, Lisbeth; Fritzson, Ingela; Pekarski, Olga; Runstroem, Anna; Sandin, Helena; Thuvesson, Ingela; Bjoerk, Anders Journal of Medicinal Chemistry, 2004 , vol. 47, # 8 p. 2075 - 2088

~%

5-氯-1,2-二氢-4-羟基-1-甲基-2-氧代-3-喹啉羧酸乙酯结构式

5-氯-1,2-二氢-4-羟基...

248282-10-2

文献:Joensson, Stig; Andersson, Gunnar; Fex, Tomas; Fristedt, Tomas; Hedlund, Gunnar; Jansson, Karl; Abramo, Lisbeth; Fritzson, Ingela; Pekarski, Olga; Runstroem, Anna; Sandin, Helena; Thuvesson, Ingela; Bjoerk, Anders Journal of Medicinal Chemistry, 2004 , vol. 47, # 8 p. 2075 - 2088

 英文别名

ETHYL-5-CHLORO-1,2-DIHYDRO-4-HYDROXY-1-METHYL-2-OXO-3-QUINOLINE CARBOXYLATE
1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxylic acid ethyl ester
5-chloro-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-3-quinolinecarboxylic acid ethyl ester
ethyl 5-chloro-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate
3-Quinolinecarboxylicacid,5-chloro-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-,ethyl ester
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