阿扎吩

• 常用名: 阿扎吩
• 英文名: Azaphen
• CAS号: 24853-80-3
• 分子量: 370.27700
• 密度: N/A
• 沸点: 536ºC at 760 mmHg
• 分子式: C₁₆H₂₁Cl₂N₅O
• 熔点: N/A
• 闪点: 278ºC

阿扎吩用途

Pipofezine(Azafen,Azaphen)是5-羟色胺重吸收抑制剂。

阿扎吩名称

• 中文名: 阿扎吩
• 英文名: 5-methyl-3-(4-methylpiperazin-1-yl)pyridazino[3,4-b][1,4]benzoxazine,dihydrochloride
• 中文别名: 2-(4-甲基-1-哌嗪基)-10-甲基-3,4-二氮吩嗪二盐酸盐

阿扎吩生物活性

• 描述: Pipofezine(Azafen,Azaphen)是5-羟色胺重吸收抑制剂。
• 相关类别:
  信号通路 >> 神经信号通路 >> 5-羟色胺转运蛋白
  研究领域 >> 神经疾病
  天然产物 >> 生物碱
• 参考文献:

  [1]. Domestic antidepressants. 1. Azaphen By Andreeva, N. I.; Asnina, V. V.; Liberman, S. S. From Pharmaceutical Chemistry Journal (Translation of Khimiko-Farmatsevticheskii Zhurnal) (2000), 34(5), 237-241.

  [2]. Shinaev NN, Akzhigitov RG. Azaphen: a return to clinical practice.Zh Nevrol Psikhiatr Im S S Korsakova. 2005;105(10):55-6.

  [3]. Ignatowicz L, Ignatowicz R, Wdowiak MW, Jaremko A. Azaphen in the treatment of enuresis in children.Psychiatr Pol. 1977 Jan-Feb;11(1):29-33.

  [4]. Liberman SS, Sharova SA. A comparison of the effect of the tricyclic antidepressants azaphen and imizin on the gastrointestinal tracts of experimental animals.Farmakol Toksikol. 1975 Jan-Feb;38(1):29-32.

  [5]. Misurec J, Náhunek K, Kamenická V, Chmelar M. Proceedings: Influence of azaphen, a new antidepressive drug, on the human EEG. Act Nerv Super (Praha). 1974;16(4):245-6.

阿扎吩物理化学性质

• 沸点: 536ºC at 760 mmHg
• 分子式: C₁₆H₂₁Cl₂N₅O
• 分子量: 370.27700
• 闪点: 278ºC
• 精确质量: 369.11200
• PSA: 44.73000
• LogP: 3.77390
• 蒸汽压: 1.46E-11mmHg at 25°C
• 储存条件: 通风低温干燥

阿扎吩毒性和生态

阿扎吩安全信息

• 海关编码: 2934999090

阿扎吩海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

阿扎吩英文别名

• Azaphenonxazine 2HCl
• 5-methyl-3-(4-methyl-piperazin-1-yl)-5H-benzo[b]pyridazino[4,3-e][1,4]oxazine,dihydrochloride
• 5H-Pyridazino(3,4-b)(1,4)benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-,dihydrochloride
• 5-Methyl-3-(4-methyl-1-piperazinyl)-5H-pyridazino(3,4-b)(1,4)benzoxazine dihydrochloride
• Azaphen hydrochloride
• Azafen
• 2-(4-Methyl-1-piperazinyl)-10-methyl-3,4-diazaphenoxazindihydrochlorid [German]
• pipofezine,dihydrochloride
• Pipofezin hydrochloride
• 5-methyl-3-(4-methylpiperazin-1-yl)-5h-pyridazino[3,4-b][1,4]benzoxazine dihydrochloride
• Azaphen