Tyrosinase-IN-6

• 常用名: Tyrosinase-IN-6
• 英文名: Tyrosinase-IN-6
• CAS号: 2569221-17-4
• 分子量: 393.52
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₃₁N₃O₂
• 熔点: N/A
• 闪点: N/A

Tyrosinase-IN-6用途

化合物4B被证明是最有效的酪氨酸酶抑制剂(ic50=3.80μM),它也显示出良好的抗氧化活性。

Tyrosinase-IN-6名称

• 英文名: Tyrosinase-IN-6

Tyrosinase-IN-6生物活性

• 描述: 化合物4B被证明是最有效的酪氨酸酶抑制剂(ic50=3.80μM),它也显示出良好的抗氧化活性。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 代谢酶/蛋白酶 >> 酪氨酸酶
• 参考文献:

  [1]. De Luca L,et al. Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety. Bioorg Med Chem. 2020 Jun 1;28(11):115497.

Tyrosinase-IN-6物理化学性质

• 分子式: C₂₄H₃₁N₃O₂
• 分子量: 393.52

Tyrosinase-IN-6靶点实验

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实验名称：Noncompetitive inhibition of diphenolase activity of mushroom tyrosinase assessed as ... 来源：ChEMBL 靶标：Polyphenol oxidase 4 External Id：CHEMBL4725761

实验名称：Displacement of [H3]DTG from rat liver homogenates sigma 2 receptor assessed as inhib... 来源：ChEMBL 靶标：Sigma intracellular receptor 2 External Id：CHEMBL5329909

实验名称：Cytotoxicity against human HeLa cells assessed as cell viability at 4 to 10 uM measur... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4725762

实验名称：Selectivity ratio of Ki for rat liver homogenates sigma 2 receptor assessed as inhibi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5329910

实验名称：Inhibition of diphenolase activity of mushroom tyrosinase using L-Dopa as substrate p... 来源：ChEMBL 靶标：Polyphenol oxidase 4 External Id：CHEMBL4725760

实验名称：Displacement of [3H](+)-pentazocine from rat liver homogenates sigma 1 receptor asses... 来源：ChEMBL 靶标：Sigma non-opioid intracellular receptor 1 External Id：CHEMBL5329908

实验名称：Potency index, ratio of kojic acid IC50 to test compound IC50 for diphenolase activit... 来源：ChEMBL 靶标：Polyphenol oxidase 4 External Id：CHEMBL4725764

实验名称：Binding affinity to human Tyrosinase assessed as gibbs free energy change by MM-GBSA ... 来源：ChEMBL 靶标：Tyrosinase External Id：CHEMBL5628757

实验名称：Binding affinity to mushroom tyrosinase assessed as gibbs free energy change by MM-GB... 来源：ChEMBL 靶标：Polyphenol oxidase 4 External Id：CHEMBL5628758

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