MEK4 inhibitor-1

• 常用名: MEK4 inhibitor-1
• 英文名: MEK4 inhibitor-1
• CAS号: 2570386-36-4
• 分子量: 291.30
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₁₀FN₃O₂S
• 熔点: N/A
• 闪点: N/A

MEK4 inhibitor-1用途

MEK4抑制剂-1是一种新型的抗胰腺癌MEK4抑制剂,IC50值为61 nM。

MEK4 inhibitor-1名称

• 英文名: MEK4 inhibitor-1

MEK4 inhibitor-1生物活性

• 描述: MEK4抑制剂-1是一种新型的抗胰腺癌MEK4抑制剂,IC50值为61 nM。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> MAPK/ERK信号通路 >> MEK
• 参考文献:

  [1]. Kwong AJ, et al. Rational Design, Optimization, and Biological Evaluation of Novel MEK4 Inhibitors against Pancreatic Adenocarcinoma. ACS Med Chem Lett. 2021 Sep 15;12(10):1559-1567.

MEK4 inhibitor-1物理化学性质

• 分子式: C₁₃H₁₀FN₃O₂S
• 分子量: 291.30

MEK4 inhibitor-1靶点实验

查看更多实验

实验名称：Inhibition of human wild type full length MEK3 (M1 to S318) expressed in mammalian ex... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 3 External Id：CHEMBL4840158

实验名称：Inhibition of human wild type partial length MEK4 (S85 to D399 residues) expressed in... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 4 External Id：CHEMBL4840157

实验名称：Selectivity ratio of IC50 for human recombinant full length N-terminal GST tagged MEK... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4840156

实验名称：Inhibition of human wild type partial length MEK4 (S85 to D399 residues) expressed in... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 4 External Id：CHEMBL4840162

实验名称：Inhibition of human wild type full length MEK7 (M1 to R417 residues) expressed in mam... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 7 External Id：CHEMBL4840161

实验名称：Inhibition of human wild type partial length MEK6 (K36 to D344 residues) expressed in... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 6 External Id：CHEMBL4840160

实验名称：Inhibition of human wild type partial length MEK5 (L98 to P448 residues) expressed in... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 5 External Id：CHEMBL4840159

实验名称：Selectivity ratio of inhibition of human wild type partial length MEK4 (S85 to D399 r... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4840150

实验名称：Selectivity ratio of inhibition of human wild type partial length MEK4 (S85 to D399 r... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4840149

实验名称：Selectivity ratio of inhibition of human wild type partial length MEK4 (S85 to D399 r... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4840148

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