Ghrelin receptor full agonist-2

• 常用名: Ghrelin receptor full agonist-2
• 英文名: Ghrelin receptor full agonist-2
• CAS号: 2602452-73-1
• 分子量: 558.05
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₈ClN₅O₅S
• 熔点: N/A
• 闪点: N/A

Ghrelin receptor full agonist-2用途

Ghrelin受体全激动剂-2是一种高效的Ghrelin受体全激动剂。

Ghrelin receptor full agonist-2名称

• 英文名: Ghrelin receptor full agonist-2

Ghrelin receptor full agonist-2生物活性

• 描述: Ghrelin受体全激动剂-2是一种高效的Ghrelin受体全激动剂。
• 相关类别:
  研究领域 >> 代谢疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> GHSR
• 参考文献:

  [1]. Cooper M, et al. Identification and Optimization of Pyrrolidine Derivatives as Highly Potent Ghrelin Receptor Full Agonists. J Med Chem. 2020 Sep 10;63(17):9705-9730.

Ghrelin receptor full agonist-2物理化学性质

• 分子式: C₂₆H₂₈ClN₅O₅S
• 分子量: 558.05
• InChIKey: DRITZQUGSDWNJE-NYDSKATKSA-N
• SMILES: O=C(NC1CN(S(=O)(=O)c2ccccc2)CC1C(=O)NC1CCCNC1)c1cc(-c2ccccc2Cl)on1

Ghrelin receptor full agonist-2靶点实验

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实验名称：Agonist activity at dog GHSR expressed in HEK293 cells assessed as increase in IP1 ac... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626044

实验名称：Agonist activity at dog GHSR expressed in HEK293 cells assessed as increase in IP1 ac... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626043

实验名称：Half life in iv or po dosed Harlan-Han Wistar rat 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626030

实验名称：Volume of distribution at steady state in iv dosed Harlan-Han Wistar rat 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626029

实验名称：Clearance in iv or po dosed dog 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626032

实验名称：Oral bioavailability in Harlan-Han Wistar rat 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626031

实验名称：Half life in iv or po dosed dog 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626034

实验名称：Volume of distribution at steady state in iv dosed dog 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626033

实验名称：Glutathione reactivity in human microsomes assessed as covalent-adduct formation 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626036

实验名称：Oral bioavailability in dog 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626035

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