HDAC-IN-29

• 常用名: HDAC-IN-29
• 英文名: HDAC-IN-29
• CAS号: 2695593-95-2
• 分子量: 401.48
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₃N₃O₄S
• 熔点: N/A
• 闪点: N/A

HDAC-IN-29用途

HDAC-IN-29(化合物13b)是一种有效的pan-HDAC抑制剂。HDAC-IN-29具有抗肿瘤活性[1]。

HDAC-IN-29名称

• 英文名: HDAC-IN-29

HDAC-IN-29生物活性

• 描述: HDAC-IN-29(化合物13b)是一种有效的pan-HDAC抑制剂。HDAC-IN-29具有抗肿瘤活性[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> HDAC
  信号通路 >> 表观遗传学 >> HDAC
• 参考文献:

  [1]. Wang J, et al. Cysteine derivatives as acetyl lysine mimics to inhibit zinc-dependent histone deacetylases for treating cancer. Eur J Med Chem. 2021 Dec 5;225:113799.

HDAC-IN-29物理化学性质

• 分子式: C₂₀H₂₃N₃O₄S
• 分子量: 401.48

HDAC-IN-29靶点实验

查看更多实验

实验名称：Toxicity in BALB/c mouse xenografted with human A549 cells assessed as effect on body... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5056766

实验名称：Antitumor activity against human A549 cells xenografted in BALB/c mouse assessed as t... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5056765

实验名称：Antitumor activity against human A549 cells xenografted in BALB/c mouse assessed as t... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5056764

实验名称：Toxicity in BALB/c mouse xenografted with human A549 cells assessed as effect on body... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5056763

实验名称：In vivo inhibition of HDAC in BALB/c mouse xenografted with human A549 cells assessed... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5056768

实验名称：In vivo inhibition of HDAC6 in BALB/c mouse xenografted with human A549 cells assesse... 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL5056767

实验名称：Acute toxicity in BALB/c mouse assessed as effect on normal behaviour at up to 2000 m... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5056758

实验名称：Upregulation of p21 in human A549 cells up to 10 uM measured after 8 hrs by Western b... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5056757

实验名称：Half life in mouse liver microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL5056756

实验名称：Half life in human liver microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL5056755

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