Myt1-IN-3

• 常用名: Myt1-IN-3
• 英文名: Myt1-IN-3
• CAS号: 2719793-54-9
• 分子量: 337.38
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₉N₅O₂
• 熔点: N/A
• 闪点: N/A

Myt1-IN-3用途

Myt1-IN-3是一种有效的Myt1抑制剂,IC50小于10 nM(WO2021195782 A1,化合物95)[1]。

Myt1-IN-3名称

• 英文名: Myt1-IN-3

Myt1-IN-3生物活性

• 描述: Myt1-IN-3是一种有效的Myt1抑制剂,IC50小于10 nM(WO2021195782 A1,化合物95)[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Daniel Durocher, et al. Methods of using myt1 inhibitors. WO2021195782 A1.

Myt1-IN-3物理化学性质

• 分子式: C₁₈H₁₉N₅O₂
• 分子量: 337.38

Myt1-IN-3靶点实验

查看更多实验

实验名称：Inhibition of CYP2D6 (unknown origin) 来源：ChEMBL 靶标：Cytochrome P450 2D6 External Id：CHEMBL5141601

实验名称：Inhibition of CYP2C9 (unknown origin) 来源：ChEMBL 靶标：Cytochrome P450 2C9 External Id：CHEMBL5141602

实验名称：Enzymatic Assay from US Patent US20240207300: "COMBINATION THERAPIES INCLUDING MYT1 I... 来源：BindingDB 靶标：N/A External Id：BindingDB_12143_1

实验名称：Time dependent inhibition of CYP3A4 (unknown origin) assessed as IC50 shift by measur... 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL5141615

实验名称：Plasma protein binding in rat at 1 uM 来源：ChEMBL 靶标：N/A External Id：CHEMBL5141611

实验名称：Oral bioavailability in Sprague-Dawley rat at 2.5 or 5 mg/kg measured upto 24 hrs by ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5141612

实验名称：Efflux ratio of apparent permeability in human Caco-2 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL5141613

实验名称：Metabolic stability in human hepatocytes assessed as intrinsic clearance measured per... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5141614

实验名称：Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified h... 来源：ChEMBL 靶标：Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase External Id：CHEMBL5141607

实验名称：Selectivity ratio of IC50 for full length Nano-luc fused EPHB3 in human HEK-293T cell... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5141610

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