ERK5-IN-6

• 常用名: ERK5-IN-6
• 英文名: ERK5-IN-6
• CAS号: 2734916-64-2
• 分子量: 339.43
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₁N₃
• 熔点: N/A
• 闪点: N/A

ERK5-IN-6用途

ERK5-IN-6 (compound 5J) 是一种具有抗癌活性的 ERK5 激酶抑制剂。ERK5-IN-6 对 A549 细胞表现出良好的抗增殖活性,IC50 值为 4.56 µg/mL。

ERK5-IN-6名称

• 英文名: ERK5-IN-6

ERK5-IN-6生物活性

• 描述: ERK5-IN-6 (compound 5J) 是一种具有抗癌活性的 ERK5 激酶抑制剂。ERK5-IN-6 对 A549 细胞表现出良好的抗增殖活性,IC50 值为 4.56 µg/mL。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> MAPK/ERK信号通路 >> ERK
  信号通路 >> 干细胞及 Wnt 通路 >> ERK
• 靶点实验:

  ERK

• 参考文献:

  [1]. Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503.

ERK5-IN-6物理化学性质

• 分子式: C₂₃H₂₁N₃
• 分子量: 339.43
• 储存条件: -20℃

ERK5-IN-6靶点实验

查看更多实验

实验名称：Antiproliferative activity against human A549 cells assessed as cell growth inhibitio... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5391715

实验名称：Antitumor activity against human A549 cells assessed as decrease in phosphorylation o... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5391721

实验名称：Induction of apoptosis in human A549 cells assessed as inhibition of colony formation... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5391720

实验名称：Induction of apoptosis in human A549 cells assessed as irregular cell morphology at 2... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5391719

实验名称：Induction of apoptosis in human A549 cells assessed as formation of apoptotic bodies ... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5391718

实验名称：Induction of apoptosis in human A549 cells assessed as chromatin condensation at 2.5 ... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5391717

实验名称：Antiproliferative activity against human A549 cells assessed as cell growth inhibitio... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5391716

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