CDK9-IN-29

• 常用名: CDK9-IN-29
• 英文名: CDK9-IN-29
• CAS号: 2737262-24-5
• 分子量: 553.60
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₃₃F₂N₅O₄
• 熔点: N/A
• 闪点: N/A

CDK9-IN-29用途

CDK9-IN-29 是一种有效的 CDK9 抑制剂 (IC50 = 3.20 nM),具有良好的激酶选择性。CDK9-IN-29 抑制细胞增殖并诱导细胞凋亡。

CDK9-IN-29名称

• 英文名: CDK9-IN-29

CDK9-IN-29生物活性

• 描述: CDK9-IN-29 是一种有效的 CDK9 抑制剂 (IC50 = 3.20 nM),具有良好的激酶选择性。CDK9-IN-29 抑制细胞增殖并诱导细胞凋亡。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> CDK
• 参考文献:

  [1]. Tizhi Wu, et al. Discovery of Selective and Potent Macrocyclic CDK9 Inhibitors for the Treatment of Osimertinib-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2023.

CDK9-IN-29物理化学性质

• 分子式: C₂₉H₃₃F₂N₅O₄
• 分子量: 553.60

CDK9-IN-29靶点实验

查看更多实验

实验名称：Toxicity in ICR mouse assessed as abnormalities in heart at 1000 mg/kg, po measured a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391923

实验名称：Toxicity in ICR mouse assessed as abnormalities in liver at 1000 mg/kg, po measured a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391922

实验名称：Toxicity in ICR mouse assessed as morphological changes in kidney at 1000 mg/kg, po m... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391921

实验名称：Toxicity in ICR mouse assessed as morphological changes in lung at 1000 mg/kg, po mea... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391920

实验名称：Toxicity in ICR mouse assessed as morphological changes in spleen at 1000 mg/kg, po m... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391919

实验名称：Toxicity in ICR mouse assessed as morphological changes in heart at 1000 mg/kg, po me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391918

实验名称：Toxicity in ICR mouse assessed as morphological changes in liver at 1000 mg/kg, po me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391917

实验名称：Toxicity in ICR mouse assessed as effect on physical appearance at 1000 mg/kg, po mea... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391916

实验名称：Toxicity in ICR mouse assessed as effect on body weight loss at 1000 mg/kg, po measur... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391915

实验名称：Toxicity in ICR mouse assessed as effect on physical appearance at 100 mg/kg, iv meas... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391914

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