DCP-LA

更新时间：2025-08-26 09:48:49

DCP-LA结构式	常用名	DCP-LA	英文名	DCP-LA
	CAS号	28399-31-7	分子量	308.50
	密度	0.969g/cm3	沸点	417.047ºC at 760 mmHg
	分子式	C₂₀H₃₆O₂	熔点	N/A
	MSDS	中文版美版	闪点	184.49ºC

DCP-LA用途

DCP-LA (FR236924) 是一种亚油酸衍生物,选择性地激活 PKCε。

中文名	DCP-LA
英文名	8-[2-[(2-pentylcyclopropyl)methyl]cyclopropyl]octanoic acid
英文别名	更多

描述	DCP-LA (FR236924) 是一种亚油酸衍生物,选择性地激活 PKCε。
相关类别	信号通路 >> 表观遗传学 >> PKC 研究领域 >> 神经疾病信号通路 >> TGF-beta/Smad 信号通路 >> PKC
靶点实验	PKCε
参考文献	[1]. Kanno T, et al. DCP-LA Activates Cytosolic PKCε by Interacting with the Phosphatidylserine Binding/Associating Sites Arg50 and Ile89 in the C2-Like Domain. Cell Physiol Biochem. 2015;37(1):193-200.

密度	0.969g/cm3
沸点	417.047ºC at 760 mmHg
分子式	C₂₀H₃₆O₂
分子量	308.50
闪点	184.49ºC
精确质量	308.27200
PSA	37.30000
LogP	6.04430
InChIKey	CONYTTFKIUJZOF-UHFFFAOYSA-N
SMILES	CCCCCC1CC1CC1CC1CCCCCCCC(=O)O
蒸汽压	0mmHg at 25°C
折射率	1.491
储存条件	2-8℃

DCP-LAMSDS英文版

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport

The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly binding to the phosphatidylserine binding site.

J. Lipid Res. 47 , 1146-1156, (2006)

This study examined the effect of 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA), a newly synthesized linoleic acid derivative with cyclopropane rings instead of cis-double bond...

Linoleic acid derivative DCP-LA improves learning impairment in SAMP8.

Neuroreport 17 , 105-108, (2006)

In the water-maze test, the linoleic acid derivative, 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) (1 mg/kg, intraperitoneally), significantly shortened the prolonged latency ...

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans...
来源：NCGC
External Id：MTASE-p

实验名称：Effect on Torpedo nicotinic ACh receptor responses at 0 min determined by measuring p...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL747889

实验名称：Effect on Torpedo nicotinic ACh receptor responses at 10 min determined by measuring ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL748730

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i...
来源：NCGC
External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i...
来源：NCGC
External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ...
来源：NCGC
External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Intraperitoneal dose required to facilitate the hippocampal neurotransmission in rat
来源：ChEMBL
靶标：Rattus norvegicus
External Id：CHEMBL776005

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) naive MV4-11 ce...
来源：NCGC
External Id：s-sky_synergy-MV-411_N-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
来源：NCGC
External Id：APP-Toga-CHIKV-nsp2-p

实验名称：Primary qHTS for Inhibitors of N-terminal methyltransferase 1 (NTMT1): MTaseGlo Assay
来源：NCGC
External Id：NTMT1-p-MTaseGlo

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Clobenpropit dihydrobromide

DCP-LA