DCP-LA

更新时间：2024-01-11 11:12:09

DCP-LA结构式	常用名	DCP-LA	英文名	DCP-LA
	CAS号	28399-31-7	分子量	308.50
	密度	0.969g/cm3	沸点	417.047ºC at 760 mmHg
	分子式	C₂₀H₃₆O₂	熔点	N/A
	MSDS	中文版美版	闪点	184.49ºC

DCP-LA用途

DCP-LA (FR236924) 是一种亚油酸衍生物,选择性地激活 PKCε。

中文名	DCP-LA
英文名	8-[2-[(2-pentylcyclopropyl)methyl]cyclopropyl]octanoic acid
英文别名	更多

描述	DCP-LA (FR236924) 是一种亚油酸衍生物,选择性地激活 PKCε。
相关类别	信号通路 >> 表观遗传学 >> PKC 研究领域 >> 神经疾病信号通路 >> TGF-beta/Smad 信号通路 >> PKC
靶点	PKCε
参考文献	[1]. Kanno T, et al. DCP-LA Activates Cytosolic PKCε by Interacting with the Phosphatidylserine Binding/Associating Sites Arg50 and Ile89 in the C2-Like Domain. Cell Physiol Biochem. 2015;37(1):193-200.

密度	0.969g/cm3
沸点	417.047ºC at 760 mmHg
分子式	C₂₀H₃₆O₂
分子量	308.50
闪点	184.49ºC
精确质量	308.27200
PSA	37.30000
LogP	6.04430
蒸汽压	0mmHg at 25°C
折射率	1.491
储存条件	2-8℃

DCP-LAMSDS英文版

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport

The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly binding to the phosphatidylserine binding site.

J. Lipid Res. 47 , 1146-1156, (2006)

This study examined the effect of 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA), a newly synthesized linoleic acid derivative with cyclopropane rings instead of cis-double bond...

Linoleic acid derivative DCP-LA improves learning impairment in SAMP8.

Neuroreport 17 , 105-108, (2006)

In the water-maze test, the linoleic acid derivative, 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) (1 mg/kg, intraperitoneally), significantly shortened the prolonged latency ...

Clobenpropit dihydrobromide

DCP-LA