荷包牡丹碱

• 常用名: 荷包牡丹碱
• 英文名: (+)-Dicentrine
• CAS号: 28832-07-7
• 分子量: 339.385
• 密度: 1.3±0.1 g/cm3
• 沸点: 480.7±45.0 °C at 760 mmHg
• 分子式: C₂₀H₂₁NO₄
• 熔点: N/A
• 闪点: 142.7±25.9 °C

荷包牡丹碱用途

Dicentrine, (-)- is an aporphinic alkaloid found in several plant species, mainly from Lauraceae family, which showed significant antinociceptive activity in an acute model of visceral pain in mice. It has also been shown to reduce spontaneous nociception and attenuating mechanical and cold hypersensitivity, probably via a TRPA1-dependent mechanism.

荷包牡丹碱名称

本表展示该化学物质的中文名称、英文系统名、各类中文与英文别名信息。

• 中文名: 荷包牡丹碱
• 英文名: 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (R)
• 中文别名: L-荷包牡丹碱

荷包牡丹碱物理化学性质

本表包含该物质理化参数，如熔点、沸点、密度、溶解度、旋光性等理化指标，无数据项标记为N/A。

• 密度: 1.3±0.1 g/cm3
• 沸点: 480.7±45.0 °C at 760 mmHg
• 分子式: C₂₀H₂₁NO₄
• 分子量: 339.385
• 闪点: 142.7±25.9 °C
• 精确质量: 339.147064
• PSA: 40.16000
• LogP: 3.98
• InChIKey: YJWBWQWUHVXPNC-CQSZACIVSA-N
• SMILES: COc1cc2c(cc1OC)-c1c3c(cc4c1C(C2)N(C)CC4)OCO3
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.616
• 储存条件: -20°C，密闭，干燥

荷包牡丹碱靶点实验

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本表记录该化合物靶点、体外体内实验、生物测定实验相关实验数据。

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

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荷包牡丹碱英文别名

本表罗列该化合物全部英文别名、系统命名、CAS别名等英文名称集合。

• (7aS)-10,11-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
• Dicentrine
• DICENTRINE- (+)
• d-Dicentrine
• O-methyl-phanostenine
• Eximine
• L-DICENTRINE

荷包牡丹碱常见问题

本部分为该化合物相关常见问答，包含基础参数、性状、储存条件等高频咨询问题与对应答案。

Q: 荷包牡丹碱的储存条件是什么？

A: 荷包牡丹碱储存条件：-20°C，密闭，干燥。

Q: 荷包牡丹碱有哪些英文别名？

A: 荷包牡丹碱英文别名有：(7aS)-10,11-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline、Dicentrine、DICENTRINE- (+)、d-Dicentrine、O-methyl-phanostenine、Eximine、L-DICENTRINE。

Q: 荷包牡丹碱有什么用途？

A: 荷包牡丹碱主要用途：Dicentrine, (-)- is an aporphinic alkaloid found in several plant species, mainly from Lauraceae family, which showed significant antinociceptive activity in an acute model of visceral pain in mice. It has also been shown to reduce spontaneous nociception and attenuating mechanical and cold hypersensitivity, probably via a TRPA1-dependent mechanism.

Q: 荷包牡丹碱的LogP（油水分配系数）是多少？

A: 荷包牡丹碱LogP（油水分配系数）为3.98。

Q: 荷包牡丹碱的极性表面积PSA是多少？

A: 荷包牡丹碱极性表面积PSA为40.16000。

Q: 荷包牡丹碱的CAS号是多少？

A: 荷包牡丹碱CAS号为28832-07-7。

Q: 荷包牡丹碱的沸点是多少？

A: 荷包牡丹碱沸点为480.7±45.0 °C at 760 mmHg。

Q: 荷包牡丹碱的分子量是多少？

A: 荷包牡丹碱分子量为339.385。

Q: 荷包牡丹碱的上游原料有哪些？

A: 荷包牡丹碱相关上游原料（CAS）：25368-02-9。

Q: 荷包牡丹碱有哪些中文别名？

A: 荷包牡丹碱中文别名有：L-荷包牡丹碱。

荷包牡丹碱生产厂家

本表列出该化合物相关生产厂商、供应商信息，包含厂家名称、产品供应相关参考信息。

上海阿拉丁生化科技股份有限公司

四川恒诚致远生物科技有限公司

上海化源世纪贸易有限公司