(+)-Dicentrine

Modify Date: 2024-01-06 17:13:59

(+)-Dicentrine Structure
(+)-Dicentrine structure
Common Name (+)-Dicentrine
CAS Number 28832-07-7 Molecular Weight 339.385
Density 1.3±0.1 g/cm3 Boiling Point 480.7±45.0 °C at 760 mmHg
Molecular Formula C20H21NO4 Melting Point N/A
MSDS N/A Flash Point 142.7±25.9 °C

 Use of (+)-Dicentrine


Dicentrine, (-)- is an aporphinic alkaloid found in several plant species, mainly from Lauraceae family, which showed significant antinociceptive activity in an acute model of visceral pain in mice. It has also been shown to reduce spontaneous nociception and attenuating mechanical and cold hypersensitivity, probably via a TRPA1-dependent mechanism.

 Names

Name 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (R)
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 480.7±45.0 °C at 760 mmHg
Molecular Formula C20H21NO4
Molecular Weight 339.385
Flash Point 142.7±25.9 °C
Exact Mass 339.147064
PSA 40.16000
LogP 3.98
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.616

 Synthetic Route

~%

(+)-Dicentrine Structure

(+)-Dicentrine

CAS#:28832-07-7

Literature: Tomita; Sirai Yakugaku Zasshi, 1943 , vol. 63, p. 233 Chem.Abstr., 1951 , p. 3399

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

(7aS)-10,11-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
Dicentrine
DICENTRINE- (+)
5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (S)-
d-Dicentrine
O-methyl-phanostenine
Eximine
5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (7aS)-
L-DICENTRINE
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