6-{吗啉-4-基[4-(三氟甲基)苯基]甲基}-1,3-二噁茚-5-醇

• 常用名: 6-{吗啉-4-基[4-(三氟甲基)苯基]甲基}-1,3-二噁茚-5-醇
• 英文名: RDR 03785
• CAS号: 289657-30-3
• 分子量: 381.35
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₈F₃NO₄
• 熔点: N/A
• 闪点: N/A

用途

RDR 03785是一种共价MIF抑制剂,其IC50为0.36μM[1]。

名称

• 中文名: 6-{吗啉-4-基[4-(三氟甲基)苯基]甲基}-1,3-二噁茚-5-醇
• 英文名: 6-{morpholin-4-yl[4-(trifluoromethyl)phenyl]methyl}-1,3-dioxaindan-5-ol

生物活性

• 描述: RDR 03785是一种共价MIF抑制剂,其IC50为0.36μM[1]。
• 相关类别:
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Cisneros JA, et al. Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2764-2767.

物理化学性质

• 分子式: C₁₉H₁₈F₃NO₄
• 分子量: 381.35
• InChIKey: AWQPMEGCCWPTRI-UHFFFAOYSA-N
• SMILES: Oc1cc2c(cc1C(c1ccc(C(F)(F)F)cc1)N1CCOCC1)OCO2
• 储存条件: 室温

靶点实验

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