Chitin synthase inhibitor 13

• 常用名: Chitin synthase inhibitor 13
• 英文名: Chitin synthase inhibitor 13
• CAS号: 2925228-79-9
• 分子量: 453.47
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₁₉N₅O₅S
• 熔点: N/A
• 闪点: N/A

Chitin synthase inhibitor 13用途

Chitin synthase inhibitor 13 (compound 12g) 是一种几丁质合酶的非竞争性抑制剂,IC50 值为 106.7 μM。 Chitin synthase inhibitor 13 具有广谱抗真菌活性。

Chitin synthase inhibitor 13名称

• 英文名: Chitin synthase inhibitor 13

Chitin synthase inhibitor 13生物活性

• 描述: Chitin synthase inhibitor 13 (compound 12g) 是一种几丁质合酶的非竞争性抑制剂,IC50 值为 106.7 μM。 Chitin synthase inhibitor 13 具有广谱抗真菌活性。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
• 参考文献:

  [1]. Du C, et, al. Design, synthesis and biological evaluation of novel spiro-quinazolinone derivatives as chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2023 Jul 5;255:115388.

Chitin synthase inhibitor 13物理化学性质

• 分子式: C₂₁H₁₉N₅O₅S
• 分子量: 453.47
• InChIKey: HVBITJXHJATQKU-BQYQJAHWSA-N
• SMILES: O=C(C=CC(=O)Nc1ccc2c(c1)C(=O)NC1(CCSC1)N2)Nc1ccc([N+](=O)[O-])cc1

Chitin synthase inhibitor 13靶点实验

查看更多实验

实验名称：Cytotoxicity against human A549 cells assessed as cell viability at 16 ug/ml incubate... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5365603

实验名称：Cytotoxicity against human A549 cells assessed as cell viability at 32 ug/ml incubate... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5365604

实验名称：Cytotoxicity against human A549 cells assessed as cell viability at 4 ug/ml incubated... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5365601

实验名称：Cytotoxicity against human A549 cells assessed as cell viability at 8 ug/ml incubated... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5365602

实验名称：Synergistic antifungal activity against Cryptococcus neoformans ATCC 32719 assessed a... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL5365653

实验名称：Synergistic antifungal activity against Aspergillus flavus ATCC 16870 assessed as fra... 来源：ChEMBL 靶标：Aspergillus flavus External Id：CHEMBL5365651

实验名称：Synergistic antifungal activity against Cryptococcus neoformans ATCC 32719 assessed a... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL5365649

实验名称：Synergistic antifungal activity against Aspergillus flavus ATCC 16870 assessed as fra... 来源：ChEMBL 靶标：Aspergillus flavus External Id：CHEMBL5365647

实验名称：Antifungal activity against Cryptococcus neoformans ATCC 32719 assessed as inhibition... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL5365645

实验名称：Synergistic antifungal activity against Candida albicans ATCC 76615 assessed as fract... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL5365646

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