Friedelin 3,4-lactone

• 常用名: Friedelin 3,4-lactone
• 英文名: Friedelin 3,4-lactone
• CAS号: 29621-75-8
• 分子量: 442.72
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₅₀O₂
• 熔点: N/A
• 闪点: N/A

Friedelin 3,4-lactone用途

Friedelin-3,4-内酯(化合物4)是一种三萜类化合物,可从巴豆叶中分离得到,抗肿瘤活性较弱[1]。

Friedelin 3,4-lactone名称

• 英文名: 3,4-secofriedelan-3 [*] 4-olide

Friedelin 3,4-lactone生物活性

• 描述: Friedelin-3,4-内酯(化合物4)是一种三萜类化合物,可从巴豆叶中分离得到,抗肿瘤活性较弱[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 体外研究: Friedelin-3,4-内酯(化合物4)对 U251细胞具有细胞毒性,IC50为 17.1微米[1]
• 参考文献:

  [1]. Reyes BM, et al. Triterpenes from Garcia parviflora. Cytotoxic evaluation of natural and semisynthetic friedelanes. J Nat Prod. 2010 Nov 29;73(11):1839-45.

Friedelin 3,4-lactone物理化学性质

• 分子式: C₃₀H₅₀O₂
• 分子量: 442.72
• 精确质量: 442.38100
• PSA: 26.30000
• LogP: 8.18350
• InChIKey: UYYLYVBSUPHXSX-PFTFKKIYSA-N
• SMILES: CC1OC(=O)CCC2C1(C)CCC1C2(C)CCC2(C)C3CC(C)(C)CCC3(C)CCC12C
• 外观性状: 粉末
• 储存条件: 室温

Friedelin 3,4-lactone靶点实验

查看更多实验

实验名称：Antiviral activity against Hepatitis B virus infected in human HepG2.215 cells assess... 来源：ChEMBL 靶标：Hepatitis B virus External Id：CHEMBL4223280

实验名称：Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL1647575

实验名称：Antiviral activity against Hepatitis B virus infected in human HepG2.215 cells assess... 来源：ChEMBL 靶标：Hepatitis B virus External Id：CHEMBL4223279

实验名称：Cytotoxicity against human SK-LU-1 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：SK-LU-1 External Id：CHEMBL1647576

实验名称：Selectivity index, ratio of CC50 for human HepG2.215 cells to IC50 for Hepatitis B vi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4223282

实验名称：Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL1647577

实验名称：Cytotoxicity against human HepG2.215 cells assessed as reduction in cell viability af... 来源：ChEMBL 靶标：HepG2 2.2.15 External Id：CHEMBL4223281

实验名称：Selectivity index, ratio of CC50 for human HepG2.215 cells to IC50 for Hepatitis B vi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4223283

实验名称：Cytotoxicity against human K562 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：K562 External Id：CHEMBL1647573

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Friedelin 3,4-lactone英文别名

• Friedelalacton
• 3,4-seco-friedelan-4,3-olide
• 4-Oxa-A-homo-friedelan-3-on
• 4-oxa-A-homo-friedelan-3-one
• Friedelolactone
• 3a-oxa-3a-homofriedelan-3-one