绿原酸甲酯

• 常用名: 绿原酸甲酯
• 英文名: Methyl chlorogenate
• CAS号: 29708-87-0
• 分子量: 368.34
• 密度: 1.5±0.1 g/cm3
• 沸点: 577.0±50.0 °C at 760 mmHg
• 分子式: C₁₇H₂₀O₉
• 熔点: N/A
• 闪点: 208.1±23.6 °C

绿原酸甲酯用途

Methyl chlorogenate 是一种抗氧化剂,具有自由基清除活性。Methyl chlorogenate 是一种抗炎剂。Methyl chlorogenate 还抑制肝细胞癌 (HCC) 细胞增殖和转移。

绿原酸甲酯名称

• 中文名: 绿原酸甲酯
• 英文名: E6GC3KV7JK

绿原酸甲酯生物活性

• 描述: Methyl chlorogenate 是一种抗氧化剂,具有自由基清除活性。Methyl chlorogenate 是一种抗炎剂。Methyl chlorogenate 还抑制肝细胞癌 (HCC) 细胞增殖和转移。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Szymborska K, et al. Extraction with Acidified Methanol-An Easy and Effective Method of Methyl Chlorogenate Formation, as Studied by ESI-MS. Molecules. 2022 Nov 3;27(21):7543.

  [2]. Pang Y, et al. Inhibition of abnormally activated HIF-1α-GLUT1/3-glycolysis pathway enhances the sensitivity of hepatocellular carcinoma to 5-caffeoylquinic acid and its derivatives. Eur J Pharmacol. 2022 Apr 5;920:174844.

绿原酸甲酯物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 577.0±50.0 °C at 760 mmHg
• 分子式: C₁₇H₂₀O₉
• 分子量: 368.34
• 闪点: 208.1±23.6 °C
• 精确质量: 368.110718
• LogP: 0.31
• InChIKey: MZNIJRAPCCELQX-SMKXDYDZSA-N
• SMILES: COC(=O)C1(O)CC(O)C(O)C(OC(=O)C=Cc2ccc(O)c(O)c2)C1
• 外观性状: 粉末
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.646
• 储存条件: 2-8℃

绿原酸甲酯靶点实验

查看更多实验

实验名称：Inhibition of human recombinant MMP12 catalytic domain incubated for 20 mins by fluor... 来源：ChEMBL 靶标：Macrophage metalloelastase External Id：CHEMBL2051216

实验名称：Inhibition of human recombinant MMP13 catalytic domain incubated for 20 mins by fluor... 来源：ChEMBL 靶标：Collagenase 3 External Id：CHEMBL2051217

实验名称：Inhibition of human recombinant MMP3 catalytic domain incubated for 20 mins by fluori... 来源：ChEMBL 靶标：Stromelysin-1 External Id：CHEMBL2051214

实验名称：Inhibition of human recombinant MMP9 catalytic domain incubated for 20 mins by fluori... 来源：ChEMBL 靶标：Matrix metalloproteinase-9 External Id：CHEMBL2051215

实验名称：Inhibition of human recombinant MMP3 catalytic domain at 10 uM incubated for 20 mins ... 来源：ChEMBL 靶标：Stromelysin-1 External Id：CHEMBL2051220

实验名称：Inhibition of human DPP4 using H-Gly-Pro-AMC peptide substrate assessed as increase i... 来源：ChEMBL 靶标：Dipeptidyl peptidase 4 External Id：CHEMBL3224678

实验名称：Inhibition of human recombinant MMP2 catalytic domain at 10 uM incubated for 20 mins ... 来源：ChEMBL 靶标：72 kDa type IV collagenase External Id：CHEMBL2051219

实验名称：Inhibition of human recombinant MMP1 catalytic domain incubated for 20 mins by fluori... 来源：ChEMBL 靶标：Interstitial collagenase External Id：CHEMBL2051212

实验名称：Inhibition of human recombinant MMP2 catalytic domain incubated for 20 mins by fluori... 来源：ChEMBL 靶标：72 kDa type IV collagenase External Id：CHEMBL2051213

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绿原酸甲酯英文别名

• Methyl (1S,3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylate
• Chlorogenic acid methyl ester, Methyl (1S,3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylate
• Methyl (1S,3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylate
• E6GC3KV7JK
• Methyl chlorogenate