Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate

• 常用名: Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate
• 英文名: Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate
• CAS号: 297159-83-2
• 分子量: 367.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₇NO₄S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate

物理化学性质

• 分子式: C₂₀H₁₇NO₄S
• 分子量: 367.4
• InChIKey: FBLHNBBDGFFXMD-QHOMEFQRSA-N
• SMILES: CCOC(=O)C1=C(/C(=C/C2=CC(=CC=C2)O)/SC1=NC3=CC=CC=C3)O

靶点实验

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实验名称：Antiproliferative activity against human JAR cells assessed as cell growth inhibition... 来源：ChEMBL 靶标：JAR External Id：CHEMBL5135116

实验名称：Antiproliferative activity against human A549 cells assessed as cell growth inhibitio... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5135118

实验名称：Antiproliferative activity against human MCF7 cells assessed as cell growth inhibitio... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL5135119

实验名称：Binding affinity to RNase L (unknown origin) expressed in Escherichia coli BL21 (DE3)... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5135115

实验名称：Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probe 来源：ChEMBL 靶标：2-5A-dependent ribonuclease External Id：CHEMBL929127

实验名称：Induction of dimerization of human RNaseL at 0.06 to 0.25 uM assessed by Western blot... 来源：ChEMBL 靶标：2-5A-dependent ribonuclease External Id：CHEMBL929128

实验名称：Induction of dimerization of human RNaseL at 3 to 12 uM assessed by Western blotting 来源：ChEMBL 靶标：2-5A-dependent ribonuclease External Id：CHEMBL929129

实验名称：Antiviral activity against encephalomyocarditis virus in wild type mouse fibroblasts ... 来源：ChEMBL 靶标：Encephalomyocarditis virus External Id：CHEMBL929130

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：Activation of human recombinant RNaseL at 40 uM assessed as cleavage of FRET RNA prob... 来源：ChEMBL 靶标：2-5A-dependent ribonuclease External Id：CHEMBL929126

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