Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate

Modify Date: 2026-04-08 14:13:37

Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate Structure
Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate structure
Common Name Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate
CAS Number 297159-83-2 Molecular Weight 367.4
Density N/A Boiling Point N/A
Molecular Formula C20H17NO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name Ethyl (Z)-5-(3-hydroxybenzylidene)-4-oxo-2-(phenylamino)-4,5-dihydrothiophene-3-carboxylate

 Chemical & Physical Properties

Molecular Formula C20H17NO4S
Molecular Weight 367.4
InChIKey FBLHNBBDGFFXMD-QHOMEFQRSA-N
SMILES CCOC(=O)C1=C(/C(=C/C2=CC(=CC=C2)O)/SC1=NC3=CC=CC=C3)O

 Bioassay

View more

Name: Antiproliferative activity against human JAR cells assessed as cell growth inhibition...
Source: ChEMBL
Target: JAR
External Id: CHEMBL5135116
Name: Antiproliferative activity against human A549 cells assessed as cell growth inhibitio...
Source: ChEMBL
Target: A549
External Id: CHEMBL5135118
Name: Antiproliferative activity against human MCF7 cells assessed as cell growth inhibitio...
Source: ChEMBL
Target: MCF7
External Id: CHEMBL5135119
Name: Binding affinity to RNase L (unknown origin) expressed in Escherichia coli BL21 (DE3)...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5135115
Name: Activation of human recombinant Rnase L assessed as cleavage of FRET RNA probe
Source: ChEMBL
Target: 2-5A-dependent ribonuclease
External Id: CHEMBL929127
Name: Induction of dimerization of human RNaseL at 0.06 to 0.25 uM assessed by Western blot...
Source: ChEMBL
Target: 2-5A-dependent ribonuclease
External Id: CHEMBL929128
Name: Induction of dimerization of human RNaseL at 3 to 12 uM assessed by Western blotting
Source: ChEMBL
Target: 2-5A-dependent ribonuclease
External Id: CHEMBL929129
Name: Antiviral activity against encephalomyocarditis virus in wild type mouse fibroblasts ...
Source: ChEMBL
Target: Encephalomyocarditis virus
External Id: CHEMBL929130
Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
Name: Activation of human recombinant RNaseL at 40 uM assessed as cleavage of FRET RNA prob...
Source: ChEMBL
Target: 2-5A-dependent ribonuclease
External Id: CHEMBL929126
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