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IRAK-4 protein kinase inhibitor 2

更新时间:2025-09-23 18:51:29

IRAK-4 protein kinase inhibitor 2结构式
IRAK-4 protein kinase inhibitor 2结构式
品牌特惠专场
常用名 IRAK-4 protein kinase inhibitor 2 英文名 IRAK-4 protein kinase inhibitor 2
CAS号 301675-24-1 分子量 282.25400
密度 N/A 沸点 N/A
分子式 C14H10N4O3 熔点 N/A
MSDS N/A 闪点 N/A

 IRAK-4 protein kinase inhibitor 2名称

英文名 N-(1H-Benzimidazol-2-yl)-3-nitrobenzamide
英文别名 更多

 IRAK-4 protein kinase inhibitor 2物理化学性质

分子式 C14H10N4O3
分子量 282.25400
精确质量 282.07500
PSA 107.09000
LogP 3.63060
InChIKey QPKROMNIEAEFQA-UHFFFAOYSA-N
SMILES O=C(Nc1nc2ccccc2[nH]1)c1cccc([N+](=O)[O-])c1

 IRAK-4 protein kinase inhibitor 2合成线路

~84%

IRAK-4 protein kinase inhibitor 2结构式

IRAK-4 protein ...

301675-24-1

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文献:GLAXOSMITHKLINE LLC; LAFRANCE, Louis, Vincent; LEBER, Jack, Dale; LI, Mei; VERMA, Sharad, Kumar Patent: WO2010/126922 A1, 2010 ; Location in patent: Page/Page column 18 ; WO 2010/126922 A1

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文献:Tularik, Inc Patent: US2003/144286 A1, 2003 ;

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IRAK-4 protein kinase inhibitor 2结构式

IRAK-4 protein ...

301675-24-1

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文献:Powers, Jay P.; Li, Shyun; Jaen, Juan C.; Liu, Jinqian; Walker, Nigel P.C.; Wang, Zhulun; Wesche, Holger Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 11 p. 2842 - 2845

 IRAK-4 protein kinase inhibitor 2上下游产品

IRAK-4 protein kinase inhibitor 2上游产品  5

IRAK-4 protein kinase inhibitor 2下游产品  0

 IRAK-4 protein kinase inhibitor 2靶点实验

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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
实验名称:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
实验名称:Inhibition of IRAK4
来源:ChEMBL
靶标:Interleukin-1 receptor-associated kinase 4
External Id:CHEMBL870864
实验名称:qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen
来源:NCGC
External Id:tdp43-p2-repeat
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 IRAK-4 protein kinase inhibitor 2英文别名

1-Ethylthymin
1-ethyl-5-methyl-1H-pyrimidine-2,4-dione
N-1H-benzimidazol-2-yl-3-nitrobenzamide
1-ethylthymine
1-Aethyl-5-methyl-1H-pyrimidin-2,4-dion
2,4(1H,3H)-Pyrimidinedione,1-ethyl-5-methyl
3-nitro-N-(1H-benzoimidazol-2-yl)-benzamide
1-ethyl-5-methyl-2,4(3H)-pyrimidindione
N1-ethylthymine
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