301675-24-1

• 常用中文名：N-(-1H-苯并[D]咪唑-2-基)-3-硝基苯甲酰胺
• 常用英文名：IRAK-4 protein kinase inhibitor 2
• CAS号：301675-24-1
• 分子式：C₁₄H₁₀N₄O₃
• 分子量：282.25400
• 发布时间：2017-06-19 21:51:17
• 更新时间：2026-10-11 14:17:47

名称

• 中文名: N-(-1H-苯并[D]咪唑-2-基)-3-硝基苯甲酰胺
• 英文名: N-(1H-Benzimidazol-2-yl)-3-nitrobenzamide
• 英文别名: N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide; 1-Aethyl-5-methyl-1H-pyrimidin-2,4-dion; N-1H-benzimidazol-2-yl-3-nitrobenzamide; 1-ethyl-5-methyl-2,4(3H)-pyrimidindione; 1-Ethylthymin; 1-ethyl-5-methyl-1H-pyrimidine-2,4-dione; Benzamide, N-1H-benzimidazol-2-yl-3-nitro; IRAK-4 protein kinase inhibitor 2, 10 mM in DMSO; 1-ethylthymine; N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide-2; 3-nitro-N-(1H-benzoimidazol-2-yl)-benzamide; N1-ethylthymine; Inhibitor,inhibit,IRAK-4,interleukin-1,IRAK-4 protein kinase inhibitor 2,immune,IRAK 4 protein kinase inhibitor 2,IRAK,Interleukin-1 rector associated kinase,inflammatory,IL-1,IL-1R associated kinase,IRAK4 protein kinase inhibitor 2; 2,4(1H,3H)-Pyrimidinedione,1-ethyl-5-methyl

物化性质

• 分子式: C₁₄H₁₀N₄O₃
• 分子量: 282.25400
• 精确质量: 282.07500
• PSA: 107.09000
• LogP: 3.63060

合成路线

934-32-7 121-92-6 ~84% 301675-24-1

文献：GLAXOSMITHKLINE LLC; LAFRANCE, Louis, Vincent; LEBER, Jack, Dale; LI, Mei; VERMA, Sharad, Kumar Patent: WO2010/126922 A1, 2010 ; Location in patent: Page/Page column 18 ; WO 2010/126922 A1

934-32-7 94790-37-1 80029-43-2 121-92-6 ~% 详细

文献：Tularik, Inc Patent: US2003/144286 A1, 2003 ;

95-54-5 ~% 301675-24-1

文献：Powers, Jay P.; Li, Shyun; Jaen, Juan C.; Liu, Jinqian; Walker, Nigel P.C.; Wang, Zhulun; Wesche, Holger Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 11 p. 2842 - 2845

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