Acetamide,N-[(7S)-10-amino-5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]

• 常用名: Acetamide,N-[(7S)-10-amino-5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]
• 英文名: Acetamide,N-[(7S)-10-amino-5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]
• CAS号: 3123-89-5
• 分子量: 384.42600
• 密度: 1.28g/cm3
• 沸点: 722.2ºC at 760 mmHg
• 分子式: C₂₁H₂₄N₂O₅
• 熔点: N/A
• 闪点: 390.6ºC

名称

• 英文名: N-[(7S)-10-amino-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

物理化学性质

• 密度: 1.28g/cm3
• 沸点: 722.2ºC at 760 mmHg
• 分子式: C₂₁H₂₄N₂O₅
• 分子量: 384.42600
• 闪点: 390.6ºC
• 精确质量: 384.16900
• PSA: 99.88000
• LogP: 3.41730
• InChIKey: JWDFWIZNGSOUGC-INIZCTEOSA-N
• SMILES: COc1cc2c(c(OC)c1OC)-c1ccc(N)c(=O)cc1C(NC(C)=O)CC2
• 折射率: 1.61

毒性和生态

靶点实验

查看更多实验

实验名称：Concentration was evaluated for its ability to inhibit microtubule assembly and prote... 来源：ChEMBL 靶标：N/A External Id：CHEMBL728391

实验名称：Cytotoxicity against human HeLa cells after 24 to 72 hrs by Cell Titer Blue assay 来源：ChEMBL 靶标：HeLa External Id：CHEMBL4668430

实验名称：NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L... 来源：DTP/NCI 靶标：N/A External Id：MCF7_OneDose

实验名称：NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell... 来源：DTP/NCI 靶标：N/A External Id：IGROV1_OneDose

实验名称：Antiproliferative activity against human COLO205 cells assessed as reduction in cell ... 来源：ChEMBL 靶标：COLO 205 External Id：CHEMBL4323669

实验名称：Antiproliferative activity against human HCT116 cells assessed as reduction in cell v... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL4323668

实验名称：Induction of P-gp in human LS180 cells assessed as increase in intracellular accumula... 来源：ChEMBL 靶标：ATP-dependent translocase ABCB1 External Id：CHEMBL4323667

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英文别名

• Colchicine amide
• Colchicein-amid
• Colchicamide
• Colchiceinamide
• Colchicamide (VAN)
• (S)--7-Acetylamino-10-amino-1,2,3-trimethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-on
• N-((S)-10-amino-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide
• 14-Aminocolchicide
• 10-demethoxy-10-N-aminocolchicine
• Colchicamid
• SKF 3192
• Colchicenamide
• Colchicide,14-amino
• N-((S)-10-Amino-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamid