异土大黄苷

• 常用名: 异土大黄苷
• 英文名: Isorhapontin
• CAS号: 32727-29-0
• 分子量: 420.41000
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₄O₉
• 熔点: N/A
• 闪点: N/A

异土大黄苷用途

异鼠李素是一种抗真菌剂。异鼠李素抑制木霉纤维二糖水解酶I(CBH I)的水解活性,Ki为57.2μM。异鼠李素还抑制木霉内切葡聚糖酶I的活性[1][2]。

异土大黄苷名称

• 中文名: 异土大黄苷
• 英文名: 3-hydroxy-5-[(1E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]phenyl β-D-glucopyranoside

异土大黄苷生物活性

• 描述: 异鼠李素是一种抗真菌剂。异鼠李素抑制木霉纤维二糖水解酶I(CBH I)的水解活性,Ki为57.2μM。异鼠李素还抑制木霉内切葡聚糖酶I的活性[1][2]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
• 靶点实验:

  Ki: 57.2 μM (Cellobiohydrolase I)[1]

• 参考文献:

  [1]. Underwood C D T, et al. Astringin and isorhapontin distribution in Sitka spruce trees. Phytochemistry, 1991, 30(7): 2183-2189.

  [2]. Shibutani S, et al. Inhibition of Trichoderma cellulase activity by a stilbene glucoside from Picea glehnii bark. Journal of wood science, 2001, 47(2): 135-140.

异土大黄苷物理化学性质

• 分子式: C₂₁H₂₄O₉
• 分子量: 420.41000
• 精确质量: 420.14200
• PSA: 149.07000
• LogP: 0.45550
• InChIKey: KLPUXMNQDCUPNO-NSCUHMNNSA-N
• SMILES: COc1cc(C=Cc2cc(O)cc(OC3OC(CO)C(O)C(O)C3O)c2)ccc1O
• 外观性状: 粉末
• 储存条件: 2-8℃

异土大黄苷靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Compound (at 100 uM) was tested for inhibition against nitric oxide production in LPS... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL734835

实验名称：Confirmatory Screen for Target Class Profiling of Small Molecule Inhibitors of Methyl... 来源：NCGC External Id：MTASE-f-cherrypicks

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) naive MV4-11 ce... 来源：NCGC External Id：s-sky_synergy-MV-411_N-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

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异土大黄苷英文别名

• isorhapontin
• isorhapontigenin-11-O-β-D-glucopyranoside
• isorhapontigenin-3-O-β-D-glucopyranoside
• isorhapontigenin 3-O-β-D-glucoside
• trans-3,4',5-Trihydroxy-3'-methoxystilben-3-O-β-D-glucopyranosid
• isorhapontigenin 3-(β-D-glucopyranoside)