4-Desacetylvinblastine
4-Desacetylvinblastine结构式
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常用名 | 4-Desacetylvinblastine | 英文名 | 4-Desacetylvinblastine |
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| CAS号 | 3352-69-0 | 分子量 | 768.93700 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C44H56N4O8 | 熔点 | 189-191℃ | |
| MSDS | N/A | 闪点 | N/A |
4-Desacetylvinblastine用途4-Desacetylvinblastine is a a pro-drug of Vinblastine. An anti-tumor agent used in the treatment of prostate cancer. |
| 英文名 | 4-O-des-acetyl vinblastine |
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| 英文别名 | 更多 |
| 熔点 | 189-191℃ |
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| 分子式 | C44H56N4O8 |
| 分子量 | 768.93700 |
| 精确质量 | 768.41000 |
| PSA | 148.03000 |
| LogP | 3.36090 |
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Tissue disposition, excretion and metabolism of vinblastine in mice as determined by high-performance liquid chromatography.
Cancer Chemother. Pharmacol. 32(4) , 286-92, (1993) We have developed and validated a selective analytical procedure, based on ion-exchange normal-phase liquid chromatography with fluorescence detection and liquid-liquid extraction, for the analysis of... |
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Disposition of the monoclonal antibody-vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine in tumor-bearing nude mice.
J. Pharmacol. Exp. Ther. 241(2) , 695-703, (1987) The monoclonal antibody-vinca alkaloid conjugate, KS1/4-DAVLB (LY256787), and free 4-desacetylvinblastine (DAVLB) were administered i.v. to male athymic nude mice bearing P3/UCLA human lung adenocarci... |
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Quantitation of human anti-mouse antibody in serum by flow cytometry.
Cytometry 13(3) , 275-81, (1992) Clinical investigations utilizing murine monoclonal antibodies require techniques for the detection of the human anti-mouse antibody (HAMA) response in patient serum. We report here a flow cytometric ... |
| 4-desacetyl vinblastine |
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