4-Desacetylvinblastine

更新时间:2024-01-16 21:50:55

4-Desacetylvinblastine结构式
4-Desacetylvinblastine结构式
委托求购
常用名 4-Desacetylvinblastine 英文名 4-Desacetylvinblastine
CAS号 3352-69-0 分子量 768.93700
密度 N/A 沸点 N/A
分子式 C44H56N4O8 熔点 189-191℃
MSDS N/A 闪点 N/A

 4-Desacetylvinblastine用途

tip
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4-Desacetylvinblastine is a a pro-drug of Vinblastine. An anti-tumor agent used in the treatment of prostate cancer.

 4-Desacetylvinblastine名称

英文名 4-O-des-acetyl vinblastine
英文别名 更多

 4-Desacetylvinblastine物理化学性质

熔点 189-191℃
分子式 C44H56N4O8
分子量 768.93700
精确质量 768.41000
PSA 148.03000
LogP 3.36090

 4-Desacetylvinblastine文献5

更多文献
Tissue disposition, excretion and metabolism of vinblastine in mice as determined by high-performance liquid chromatography.

Cancer Chemother. Pharmacol. 32(4) , 286-92, (1993)

We have developed and validated a selective analytical procedure, based on ion-exchange normal-phase liquid chromatography with fluorescence detection and liquid-liquid extraction, for the analysis of...

Disposition of the monoclonal antibody-vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine in tumor-bearing nude mice.

J. Pharmacol. Exp. Ther. 241(2) , 695-703, (1987)

The monoclonal antibody-vinca alkaloid conjugate, KS1/4-DAVLB (LY256787), and free 4-desacetylvinblastine (DAVLB) were administered i.v. to male athymic nude mice bearing P3/UCLA human lung adenocarci...

Quantitation of human anti-mouse antibody in serum by flow cytometry.

Cytometry 13(3) , 275-81, (1992)

Clinical investigations utilizing murine monoclonal antibodies require techniques for the detection of the human anti-mouse antibody (HAMA) response in patient serum. We report here a flow cytometric ...

 4-Desacetylvinblastine英文别名

4-desacetyl vinblastine