氯可托龙特戊酸酯

• 常用名: 氯可托龙特戊酸酯
• 英文名: clocortolone pivalate
• CAS号: 34097-16-0
• 分子量: 495.023
• 密度: 1.2±0.1 g/cm3
• 沸点: 598.0±50.0 °C at 760 mmHg
• 分子式: C₂₇H₃₆ClFO₅
• 熔点: N/A
• 闪点: 315.4±30.1 °C

氯可托龙特戊酸酯用途

新戊酸氯可托酮是一种合成的糖皮质激素和皮质类固醇酯。新戊酸氯考托隆适用于脂溢性皮炎、接触性皮炎、特应性皮炎和银屑病[1]。

氯可托龙特戊酸酯名称

• 中文名: 氯可托龙
• 英文名: clocortolone pivalate

氯可托龙特戊酸酯生物活性

• 描述: 新戊酸氯可托酮是一种合成的糖皮质激素和皮质类固醇酯。新戊酸氯考托隆适用于脂溢性皮炎、接触性皮炎、特应性皮炎和银屑病[1]。
• 相关类别:
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Kircik LH, et al. The treatment of inflammatory facial dermatoses with topical corticosteroids: focus on clocortolone pivalate 0.1% cream. J Drugs Dermatol. 2012 Oct;11(10):1194-8.

氯可托龙特戊酸酯物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 598.0±50.0 °C at 760 mmHg
• 分子式: C₂₇H₃₆ClFO₅
• 分子量: 495.023
• 闪点: 315.4±30.1 °C
• 精确质量: 494.223541
• PSA: 80.67000
• LogP: 4.36
• InChIKey: SXYZQZLHAIHKKY-GSTUPEFVSA-N
• SMILES: CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(Cl)C(O)CC2(C)C1C(=O)COC(=O)C(C)(C)C
• 蒸汽压: 0.0±3.8 mmHg at 25°C
• 折射率: 1.552
• 储存条件: 2-8°C

氯可托龙特戊酸酯安全信息

• 危险品运输编码: NONH for all modes of transport

氯可托龙特戊酸酯靶点实验

查看更多实验

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实验名称：MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint... 来源：Broad Institute 靶标：N/A External Id：2084-01_Activator_SinglePoint_HTS_Activity

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实验名称：qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity 来源：NCGC External Id：HERG01

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氯可托龙特戊酸酯英文别名

• (6α,11β,16α)-9-chloro-6-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate
• 9-Chloro-6a-fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-Pivalate
• Purantix
• (6α,11β,16α)-9-Chloro-6-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl pivalate
• CLODERM
• CL 68
• (6a,11b,16a)-9-Chloro-21-(2,2-dimethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
• clocortolone pivalate
• Clocortolone 21-pivalate
• 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate
• SH-863
• Propanoic acid, 2,2-dimethyl-, (6α,11β,16α)-9-chloro-6-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl ester
• Clocortolone triMethylacetate
• 9α-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate