Sipoglitazar

• 常用名: Sipoglitazar
• 英文名: Sipoglitazar
• CAS号: 342026-92-0
• 分子量: 463.55
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₅N₃O₄S
• 熔点: N/A
• 闪点: N/A

Sipoglitazar用途

Sipoglitazar 是一种有口服活性的 PPAR 激动剂。Sipoglitazar 可用于研究糖尿病。

Sipoglitazar名称

• 英文名: Sipoglitazar

Sipoglitazar生物活性

• 描述: Sipoglitazar 是一种有口服活性的 PPAR 激动剂。Sipoglitazar 可用于研究糖尿病。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> PPAR
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Nishihara M, et al. An unusual metabolic pathway of sipoglitazar, a novel antidiabetic agent: cytochrome P450-catalyzed oxidation of sipoglitazar acyl glucuronide. Drug Metab Dispos. 2012 Feb;40(2):249-58.

Sipoglitazar物理化学性质

• 分子式: C₂₅H₂₅N₃O₄S
• 分子量: 463.55
• 精确质量: 463.15700
• PSA: 114.71000
• LogP: 5.04980
• InChIKey: SRFCAWATPLCLMG-UHFFFAOYSA-N
• SMILES: CCOc1nn(Cc2ccc(OCc3csc(-c4ccccc4)n3)cc2)cc1CCC(=O)O
• 储存条件: -20°C，密闭，干燥

Sipoglitazar靶点实验

查看更多实验

实验名称：Drug metabolism in human hepatic microsomes assessed as formation of 3-(3-hydroxy-1-{... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3539002

实验名称：Drug metabolism in human hepatic microsomes assessed as formation of 3-[3-ethoxy-1-(4... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3538049

实验名称：Drug metabolism in human hepatic microsomes assessed as formation of alpha-2-O-acyl g... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3535635

实验名称：Drug metabolism in human hepatic microsomes assessed as formation of beta-1-O-acyl gl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3535634

实验名称：Drug metabolism in human hepatic microsomes assessed as elimination of compound at 10... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3535969

实验名称：Drug metabolism in human hepatic microsomes assessed as formation of 3-(3-hydroxy-1-{... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3535967

实验名称：Drug metabolism in human hepatic microsomes assessed as formation of 3-[3-ethoxy-1-(4... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3535968

实验名称：Drug metabolism in human hepatic microsomes assessed as formation of 3-[3-ethoxy-1-(4... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3538044

实验名称：Drug metabolism in human hepatic microsomes assessed as beta-1-O-acyl glucuronide con... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3535974

实验名称：Drug metabolism in human hepatic microsomes assessed as formation of 3-(3-hydroxy-1-{... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3538048

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Sipoglitazar英文别名

• 3-[3-ethoxy-1-[[4-[(2-phenyl-1,3-thiazol-4-yl)methoxy]phenyl]methyl]pyrazol-4-yl]propanoic acid