千金子二萜醇

• 常用名: 千金子二萜醇
• 英文名: Lathyrol
• CAS号: 34420-19-4
• 分子量: 334.450
• 密度: 1.2±0.1 g/cm3
• 沸点: 503.5±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₀O₄
• 熔点: N/A
• 闪点: 272.4±26.6 °C

千金子二萜醇用途

Lathyrol 是一种天然产物,具有抗癌的作用。

千金子二萜醇名称

• 中文名: 千金子二萜醇
• 英文名: Lathyrol
• 中文别名: 续随子醇

千金子二萜醇生物活性

• 描述: Lathyrol 是一种天然产物,具有抗癌的作用。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 癌症
  天然产物 >> 萜类化合物和糖苷
• 体外研究: Lathyrol在体外MCF-7/ADR乳腺癌细胞系中表现出逆转作用[1]。
• 参考文献:

  [1]. Jiao W, et al. Lathyrol diterpenes as modulators of P-glycoprotein dependent multidrug resistance: structure-activity relationship studies on Euphorbia factor L3 derivatives. J Med Chem. 2015 May 14;58(9):3720-38.

千金子二萜醇物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 503.5±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₀O₄
• 分子量: 334.450
• 闪点: 272.4±26.6 °C
• 精确质量: 334.214417
• PSA: 77.76000
• LogP: 2.69
• InChIKey: SDBITTRHSROXCY-SVSKDHLKSA-N
• SMILES: C=C1CCC2C(C=C(C)C(=O)C3(O)CC(C)C(O)C3C1O)C2(C)C
• 蒸汽压: 0.0±2.9 mmHg at 25°C
• 折射率: 1.566
• 储存条件: 2-8C

千金子二萜醇靶点实验

查看更多实验

实验名称：Cytotoxicity against human HEK293T cells assessed as reduction in cell viability at 1... 来源：ChEMBL 靶标：HEK-293T External Id：CHEMBL4836700

实验名称：Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 4... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL3428658

实验名称：Resistance index, ratio of MIC80 for Saccharomyces cerevisiae AD over-expressing Cand... 来源：ChEMBL 靶标：Saccharomyces cerevisiae External Id：CHEMBL4021812

实验名称：Synergistic antifungal activity against Saccharomyces cerevisiae AD1-8u(-) assessed a... 来源：ChEMBL 靶标：Saccharomyces cerevisiae External Id：CHEMBL4021813

实验名称：Antifungal activity against Saccharomyces cerevisiae AD over-expressing Candida albic... 来源：ChEMBL 靶标：Saccharomyces cerevisiae External Id：CHEMBL4021810

实验名称：Resistance index, ratio of MIC80 for Saccharomyces cerevisiae AD over-expressing Cand... 来源：ChEMBL 靶标：Saccharomyces cerevisiae External Id：CHEMBL4021811

实验名称：Antifungal activity against Saccharomyces cerevisiae AD1-8u(-) after 48 hrs 来源：ChEMBL 靶标：Saccharomyces cerevisiae External Id：CHEMBL4021808

实验名称：Antifungal activity against Saccharomyces cerevisiae AD over-expressing Candida albic... 来源：ChEMBL 靶标：Saccharomyces cerevisiae External Id：CHEMBL4021809

实验名称：Inhibition of Candida albicans CDR1 expressed in Saccharomyces cerevisiae AD assessed... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4021806

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL5258731

共19条，当前第1页，共2页

1

2

千金子二萜醇英文别名

• (1aR,2E,4aR,6S,7S,7aR,8R,11aS)-4a,7,8-Trihydroxy-1,1,3,6-tetramethyl-9-methylene-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-4H-cyclopenta[a]cyclopropa[f][11]annulen-4-one
• (1aR,2E,4aR,6S,7S,7aR,8R,11aS)-4a,7,8-trihydroxy-1,1,3,6-tetramethyl-9-methylidene-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-4H-cyclopenta[a]cyclopropa[f][11]annulen-4-one
• (1aS,2E,4aR,6S,7S,7aR,8R,11aS)-4a,7,8-Trihydroxy-1,1,3,6-tetramethyl-9-methylene-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-4H-cyclopenta[a]cyclopropa[f][11]annulen-4-one