Dihydrotetrabenazine

• 常用名: Dihydrotetrabenazine
• 英文名: Dihydrotetrabenazine
• CAS号: 3466-75-9
• 分子量: 319.439
• 密度: 1.1±0.1 g/cm3
• 沸点: 457.8±45.0 °C at 760 mmHg
• 分子式: C₁₉H₂₉NO₃
• 熔点: N/A
• 闪点: 230.7±28.7 °C

Dihydrotetrabenazine用途

Dihydrotetrabenazine (racemic) is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum and inhibits synaptic vesicular serotonin (5-HT) uptake. It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta. Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum.

Dihydrotetrabenazine名称

• 英文名: 9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol

Dihydrotetrabenazine物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 457.8±45.0 °C at 760 mmHg
• 分子式: C₁₉H₂₉NO₃
• 分子量: 319.439
• 闪点: 230.7±28.7 °C
• 精确质量: 319.214752
• PSA: 41.93000
• LogP: 3.17
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.562

Dihydrotetrabenazine安全信息

• 海关编码: 2933990090

Dihydrotetrabenazine海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Dihydrotetrabenazine英文别名

• 2-Hydroxy-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo(a)quinolizine
• 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-
• 3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol
• 2H-Benzo(a)quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-
• 3-isobutyl-9-methoxy-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2-ol
• 2-Hydroxytetrabenazine
• trans (2,3)-Dihydro Tetrabenazine