Dihydrotetrabenazine
Modify Date: 2024-01-11 09:09:09
Dihydrotetrabenazine structure
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Common Name | Dihydrotetrabenazine | ||
|---|---|---|---|---|
| CAS Number | 3466-75-9 | Molecular Weight | 319.439 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 457.8±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H29NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 230.7±28.7 °C | |
Use of DihydrotetrabenazineDihydrotetrabenazine (racemic) is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum and inhibits synaptic vesicular serotonin (5-HT) uptake. It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta. Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum. |
| Name | 9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol |
|---|---|
| Synonym | More Synonyms |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 457.8±45.0 °C at 760 mmHg |
| Molecular Formula | C19H29NO3 |
| Molecular Weight | 319.439 |
| Flash Point | 230.7±28.7 °C |
| Exact Mass | 319.214752 |
| PSA | 41.93000 |
| LogP | 3.17 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.562 |
| HS Code | 2933990090 |
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| Precursor 0 | |
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| DownStream 1 | |
CAS#:5220-98-4| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 2-Hydroxy-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo(a)quinolizine |
| 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)- |
| 3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol |
| 2H-Benzo(a)quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)- |
| 3-isobutyl-9-methoxy-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2-ol |
| 2-Hydroxytetrabenazine |
| trans (2,3)-Dihydro Tetrabenazine |