(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine

更新时间:2024-01-05 12:20:37

(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine结构式
(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine结构式
委托求购
常用名 (6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine 英文名 (6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine
CAS号 380499-07-0 分子量 435.33500
密度 N/A 沸点 N/A
分子式 C20H16F7NO2 熔点 N/A
MSDS N/A 闪点 N/A

 名称

英文名 (6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine

 物理化学性质

分子式 C20H16F7NO2
分子量 435.33500
精确质量 435.10700
PSA 30.82000
LogP 5.22210

 合成线路

~90%

(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine结构式

(6R)-6-[(1R)-1-...

380499-07-0

文献:Sandoz AG Patent: WO2009/106486 A1, 2009 ; Location in patent: Page/Page column 15; 4 ;

~%

(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine结构式

(6R)-6-[(1R)-1-...

380499-07-0

文献:Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C. Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747

~%

(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine结构式

(6R)-6-[(1R)-1-...

380499-07-0

文献:Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C. Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747

~%

(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine结构式

(6R)-6-[(1R)-1-...

380499-07-0

文献:Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C. Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747

~%

(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine结构式

(6R)-6-[(1R)-1-...

380499-07-0

文献:Zhao, Matthew M.; McNamara, James M.; Ho, Guo-Jie; Emerson, Khateeta M.; Song, Zhiguo J.; Tschaen, David M.; Brands, Karel M. J.; Dolling, Ulf-H; Grabowski, Edward J. J.; Reider, Paul J.; Cottrell, Ian F.; Ashwood, Michael S.; Bishop, Brian C. Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6743 - 6747