20(R)-人参皂苷Rg3

• 常用名: 20(R)-人参皂苷Rg3
• 英文名: 20(R)-Ginsenoside Rg3
• CAS号: 38243-03-7
• 分子量: 785.01
• 密度: 1.4±0.1 g/cm3
• 沸点: 1117.1±65.0 °C at 760 mmHg
• 分子式: C₄₂H₇₂O₁₃
• 熔点: 315-318ºC
• 闪点: 629.4±34.3 °C

20(R)-人参皂苷Rg3用途

20(R)-ginsenoside Rg3 (20(R)-Propanaxadiol),人参根中的一种活性化合物,具有有效的血管抑制活性和抗肿瘤活性。

20(R)-人参皂苷Rg3名称

• 中文名: 人参皂甙 Rg3
• 英文名: 20(R)-Propanaxadiol
• 中文别名: 20(R)人参皂苷Rg3 | 人参皂苷 R-RG3 | (R型)人参皂苷Rg3 | 人参皂苷 Rg3 | R-人参皂苷 Rg3 | 20(R)人参皂甙Rg3 | R型人参皂苷Rg3

20(R)-人参皂苷Rg3生物活性

• 描述: 20(R)-ginsenoside Rg3 (20(R)-Propanaxadiol),人参根中的一种活性化合物,具有有效的血管抑制活性和抗肿瘤活性。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Liu L, et al. Enzymatic preparation of 20(S, R)-protopanaxadiol by transformation of 20(S, R)-Rg3 from blackginseng. Phytochemistry. 2010 Sep;71(13):1514-20.

  [2]. Yue PY, et al. The angiosuppressive effects of 20(R)- ginsenoside Rg3. Biochem Pharmacol. 2006 Aug 14;72(4):437-45.

20(R)-人参皂苷Rg3物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 1117.1±65.0 °C at 760 mmHg
• 熔点: 315-318ºC
• 分子式: C₄₂H₇₂O₁₃
• 分子量: 785.01
• 闪点: 629.4±34.3 °C
• 精确质量: 785.01
• PSA: 357.06000
• LogP: 4.73
• InChIKey: RWXIFXNRCLMQCD-CZIWJLDFSA-N
• SMILES: CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC1C3(C)CCC(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4O)C(C)(C)C3CCC12C
• 外观性状: 固体;White to Light yellow powder to crystal
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.622
• 储存条件: 0-10°C;避免加热

20(R)-人参皂苷Rg3靶点实验

查看更多实验

实验名称：Hydroxyl radical scavenging activity at 2 mM 来源：ChEMBL 靶标：N/A External Id：CHEMBL856912

实验名称：Activation of flag-tagged SIRT1 (unknown origin) expressed in HEK293 cells after 12 h... 来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1 External Id：CHEMBL3366462

实验名称：Inhibition of SIRT1 (unknown origin) assessed as reduction in Fluor de Lys deacetylat... 来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1 External Id：CHEMBL4185127

实验名称：Activation of SIRT1 (unknown origin) assessed as Fluor de Lys deacetylation at 10 to ... 来源：ChEMBL 靶标：NAD-dependent protein deacetylase sirtuin-1 External Id：CHEMBL4185128

实验名称：Cytotoxicity against human U2OS cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：U2OS External Id：CHEMBL1787199

实验名称：Cytotoxicity against human ES2 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1787198

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Inhibition of cell proliferation of human U251 cells assessed as cell viability at 10... 来源：ChEMBL 靶标：U-251 External Id：CHEMBL3385796

实验名称：Cytotoxicity against human A549 cells assessed as cell viability at 100 uM after 48 h... 来源：ChEMBL 靶标：A549 External Id：CHEMBL1787209

实验名称：Cytotoxicity against neonatal HDF assessed as cell viability at 10 uM after 24 hrs by... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3540282

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20(R)-人参皂苷Rg3英文别名

• 20(S)-ginsenoside Rg3
• (3β,12β)-20-{[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 6-O-β-D-xylopyranosyl-α-D-glucopyranoside
• Ginsenoside Rg3 (R-)
• Ginsenoside Rg3 Rh2
• 20(R)Ginsenoside Rg3
• R-form-Ginsenoside Rg3
• GINSENOSIDE RG3(R-FORM)(P)
• (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(1R)-1-hydroxy-1,5-dimethyl-hex-4-enyl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-methylol-tetrahydropyran-3-yl]oxy-6-methylol-tetrahydropyran-3,4,5-triol
• Ginsenoside Rg3
• 20(R)-Ginsenoside-Rg3