9α,11β-PGF2(9α,11β-前列腺素F2)

• 常用名: 9α,11β-PGF2(9α,11β-前列腺素F2)
• 英文名: 9α,11β-Prostaglandin F2α
• CAS号: 38432-87-0
• 分子量: 354.481
• 密度: 1.2±0.1 g/cm3
• 沸点: 531.0±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₄O₅
• 熔点: N/A
• 闪点: 289.0±26.6 °C

用途

9α,11β-前列腺素F2α是尿中存在的内源性代谢产物,可用于哮喘的研究[1][2]。

名称

• 中文名: 11beta-前列腺素 and in f2alpha
• 英文名: 7-[(1R,2R,3S,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid

生物活性

• 描述: 9α,11β-前列腺素F2α是尿中存在的内源性代谢产物,可用于哮喘的研究[1][2]。
• 相关类别:
  研究领域 >> 炎症/免疫
• 靶点实验:

  Human Endogenous Metabolite

• 体外研究: 内源性代谢产物被定义为《京都基因和基因组百科全书》注释为我们基因组中约1900种代谢酶的底物或产物。在文献正文中很清楚,许多这些代谢产物都具有毒性[1]。
• 参考文献:

  [1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

  [2]. Mai XM, et al. Urinary inflammatory mediators and inhalation of hypertonic saline in children. Allergy. 2005 Jan;60(1):60-4.

物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 531.0±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₄O₅
• 分子量: 354.481
• 闪点: 289.0±26.6 °C
• 精确质量: 354.240631
• PSA: 97.99000
• LogP: 2.14
• InChIKey: PXGPLTODNUVGFL-DEZIHLQHSA-N
• SMILES: CCCCCC(O)C=CC1C(O)CC(O)C1CC=CCCCC(=O)O
• 蒸汽压: 0.0±3.2 mmHg at 25°C
• 折射率: 1.569

靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E... 来源：NCGC External Id：epac1-activator-v

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3... 来源：NCGC External Id：epac1-inhibitor-v

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (E... 来源：NCGC External Id：epac2-activator-v2

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4... 来源：NCGC External Id：epac2-inhibitor-v2

实验名称：Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ORF 73 [Human herpesvirus 8 type M] External Id：HMS791

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar... 来源：NCGC 靶标：67.9K protein [Vaccinia virus] External Id：Vaccinia-p2mCherry

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

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英文别名

• (5Z,9α,11β,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid