trans-Resveratrol 4'-O-β-D-glucopyranoside

• 常用名: trans-Resveratrol 4'-O-β-D-glucopyranoside
• 英文名: Resveratroloside
• CAS号: 38963-95-0
• 分子量: 404.36700
• 密度: 1.521±0.06 g/cm3
• 沸点: N/A
• 分子式: C₂₀H₂₂O₈
• 熔点: 235-238 ºC
• 闪点: N/A

用途

Resveratroloside 是一种 α-glucosidase 的竞争新抑制剂,能调节血糖水平。Resveratroloside 具有心脏保护作用。

名称

• 中文名: 白藜芦醇-4'-O-葡萄糖苷
• 英文名: (2S,3R,4S,5S,6R)-2-[4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• 中文别名: 白藜芦醇 4'-O-beta-D-吡喃葡萄糖苷

生物活性

• 描述: Resveratroloside 是一种 α-glucosidase 的竞争新抑制剂,能调节血糖水平。Resveratroloside 具有心脏保护作用。
• 相关类别:
  研究领域 >> 心血管疾病
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Zhao X, et al. Resveratroloside Alleviates Postprandial Hyperglycemia in Diabetic Mice by Competitively Inhibiting α-Glucosidase. J Agric Food Chem. 2019 Mar 13;67(10):2886-2893.

  [2]. Naumenko SE, et al. Cardioprotective effect of resveratrol and resveratroloside. Cardiovasc Hematol Agents Med Chem. 2013 Sep;11(3):207-10.

物理化学性质

• 密度: 1.521±0.06 g/cm3
• 熔点: 235-238 ºC
• 分子式: C₂₀H₂₂O₈
• 分子量: 404.36700
• 精确质量: 404.11100
• PSA: 156.91000
• LogP: 0.53920
• InChIKey: RUOKEYJFAJITAG-CUYWLFDKSA-N
• SMILES: OCC1OC(Oc2ccc(C=Cc3cc(O)cc(O)c3)cc2)C(O)C(O)C1O
• 外观性状: 固体
• 储存条件: 2-8°C，密封，干燥
• 水溶解性: Slightly soluble (1.7 g/L) (25 ºC)

靶点实验

查看更多实验

实验名称：Inhibition of rat brain PKC 来源：ChEMBL 靶标：Protein kinase C theta type External Id：CHEMBL1005271

实验名称：Inhibition of bovine thymus p56LCK 来源：ChEMBL 靶标：N/A External Id：CHEMBL1005270

实验名称：Cytotoxicity against C57BL/6 mouse B16F10 cells assessed as reduction in cell viabili... 来源：ChEMBL 靶标：B16-F10 External Id：CHEMBL4315476

实验名称：Antimelanogenic activity against C57BL/6 mouse B16F10 cells at 50 uM incubated for 72... 来源：ChEMBL 靶标：B16-F10 External Id：CHEMBL4315475

实验名称：Antiinflammatory activity in human CCD-18Co cells assessed as inhibition of IL1beta-i... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1815314

实验名称：Antimelanogenic activity against C57BL/6 mouse B16F10 cells at 10 uM incubated for 72... 来源：ChEMBL 靶标：B16-F10 External Id：CHEMBL4315474

实验名称：Antimelanogenic activity against C57BL/6 mouse B16F10 cells incubated for 10 to 50 uM... 来源：ChEMBL 靶标：B16-F10 External Id：CHEMBL4315473

实验名称：Ratio of IC50 for arbutin to IC50 for test compound for inhibition of mushroom tyrosi... 来源：ChEMBL 靶标：Polyphenol oxidase 2 External Id：CHEMBL4315483

实验名称：Antimelanogenic activity against C57BL/6 mouse B16F10 cells incubated for 72 hrs 来源：ChEMBL 靶标：B16-F10 External Id：CHEMBL4315482

实验名称：Stability of compound in IMDM cell medium incubated for 24 hrs by HPLC analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315479

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英文别名

• Resveratrol (3,4',5-trihydroxystilbene)
• trans-resveratroloside
• Resveratroloside
• GOB C
• B-D-glucopyranoside,4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl
• BIDD:ER0104
• Resveratrol 4'-Glucoside
• Resveratrol 4'-O-beta-D-glucopyranoside