STX140

• 常用名: STX140
• 英文名: STX140
• CAS号: 401600-86-0
• 分子量: 460.565
• 密度: 1.5±0.1 g/cm3
• 沸点: 644.8±65.0 °C at 760 mmHg
• 分子式: C₁₉H₂₈N₂O₇S₂
• 熔点: N/A
• 闪点: 343.8±34.3 °C

STX140用途

STX140 is a bis-sulfamate derivative of the endogenous steroid 2-methoxyestradiol, has shown promising anticancer potency both in vitro and in vivo, with excellent bioavailability. STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells. STX140 causes apoptosis via the intrinsic mitochondrial pathway and down-regulate survivin and XIAP expression in ovarian and prostate cancer cells.

STX140名称

• 英文名: STX140

STX140物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 644.8±65.0 °C at 760 mmHg
• 分子式: C₁₉H₂₈N₂O₇S₂
• 分子量: 460.565
• 闪点: 343.8±34.3 °C
• 精确质量: 460.133789
• LogP: 3.01
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.629

STX140英文别名

• STX140
• Sulfamic acid, (17β)-2-methoxyestra-1(10),2,4-triene-3,17-diyl ester
• (9β,13α,14β,17α)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE
• (17β)-2-Methoxyestra-1(10),2,4-triene-3,17-diyl disulfamate