STX140
Modify Date: 2024-08-09 14:29:32
STX140 structure
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Common Name | STX140 | ||
|---|---|---|---|---|
| CAS Number | 401600-86-0 | Molecular Weight | 460.565 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 644.8±65.0 °C at 760 mmHg | |
| Molecular Formula | C19H28N2O7S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 343.8±34.3 °C | |
Use of STX140STX140 is a bis-sulfamate derivative of the endogenous steroid 2-methoxyestradiol, has shown promising anticancer potency both in vitro and in vivo, with excellent bioavailability. STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells. STX140 causes apoptosis via the intrinsic mitochondrial pathway and down-regulate survivin and XIAP expression in ovarian and prostate cancer cells. |
| Name | STX140 |
|---|---|
| Synonym | More Synonyms |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 644.8±65.0 °C at 760 mmHg |
| Molecular Formula | C19H28N2O7S2 |
| Molecular Weight | 460.565 |
| Flash Point | 343.8±34.3 °C |
| Exact Mass | 460.133789 |
| LogP | 3.01 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.629 |
| STX140 |
| Sulfamic acid, (17β)-2-methoxyestra-1(10),2,4-triene-3,17-diyl ester |
| (9β,13α,14β,17α)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE |
| (17β)-2-Methoxyestra-1(10),2,4-triene-3,17-diyl disulfamate |