STX140

Modify Date: 2024-08-09 14:29:32

STX140 Structure
STX140 structure
Common Name STX140
CAS Number 401600-86-0 Molecular Weight 460.565
Density 1.5±0.1 g/cm3 Boiling Point 644.8±65.0 °C at 760 mmHg
Molecular Formula C19H28N2O7S2 Melting Point N/A
MSDS N/A Flash Point 343.8±34.3 °C

 Use of STX140


STX140 is a bis-sulfamate derivative of the endogenous steroid 2-methoxyestradiol, has shown promising anticancer potency both in vitro and in vivo, with excellent bioavailability. STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells. STX140 causes apoptosis via the intrinsic mitochondrial pathway and down-regulate survivin and XIAP expression in ovarian and prostate cancer cells.

 Names

Name STX140
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 644.8±65.0 °C at 760 mmHg
Molecular Formula C19H28N2O7S2
Molecular Weight 460.565
Flash Point 343.8±34.3 °C
Exact Mass 460.133789
LogP 3.01
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.629

 Synonyms

STX140
Sulfamic acid, (17β)-2-methoxyestra-1(10),2,4-triene-3,17-diyl ester
(9β,13α,14β,17α)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE
(17β)-2-Methoxyestra-1(10),2,4-triene-3,17-diyl disulfamate
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