DL-苏-beta-羟基天冬氨酸

更新时间：2024-01-02 12:56:25

DL-苏-beta-羟基天冬氨酸结构式	常用名	DL-苏-beta-羟基天冬氨酸	英文名	DL-Threo-beta-Hydroxyaspartic Acid
	CAS号	4294-45-5	分子量	149.10200
	密度	1.738 g/cm3	沸点	368.7ºC at 760 mmHg
	分子式	C₄H₇NO₅	熔点	>230ºC dec
	MSDS	中文版美版	闪点	176.8ºC

DL-苏-beta-羟基天冬氨酸用途

DL -苏式-β-羟基天冬氨酸 (THA) 是一种谷氨酸摄取抑制剂。

中文名	(2S,3S)-2-氨基-3-羟基琥珀酸
英文名	D,L-threo-β-Hydroxy Aspartic Acid
中文别名	DL-苏-beta-羟基天冬氨酸
英文别名	更多

描述	DL-threo-3-Hydroxyaspartic acid 是一种谷氨酸摄取抑制剂,可以阻断插管 SD 大鼠体内的谷氨酸转运。
相关类别	研究领域 >> 其他信号通路 >> 其他 >> 其他
参考文献	[1]. A Klegeris,et al. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells.J Neuroimmunol.1997 Sep;78(1-2):152-61. [2]. Jessica Darman, et al. Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity.J Neurosci. 2004 Aug 25;24(34):7566-75.

描述

DL-threo-3-Hydroxyaspartic acid 是一种谷氨酸摄取抑制剂,可以阻断插管 SD 大鼠体内的谷氨酸转运。

相关类别

研究领域 >> 其他

信号通路 >> 其他 >> 其他

参考文献

[1]. A Klegeris,et al. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells.J Neuroimmunol.1997 Sep;78(1-2):152-61.

[2]. Jessica Darman, et al. Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity.J Neurosci. 2004 Aug 25;24(34):7566-75.

密度	1.738 g/cm3
沸点	368.7ºC at 760 mmHg
熔点	>230ºC dec
分子式	C₄H₇NO₅
分子量	149.10200
闪点	176.8ºC
精确质量	149.03200
PSA	120.85000
外观性状	灰白色固体
折射率	1.583
储存条件	20°C

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport
海关编码	2922509090

DL-苏-beta-羟基天冬氨酸上游产品 0
DL-苏-beta-羟基天冬氨酸下游产品 2
CAS号1113-60-6 羟基丙酮酸 CAS号133-37-9 DL-酒石酸

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

The SLC1 high-affinity glutamate and neutral amino acid transporter family.

Mol. Aspects Med. 34(2-3) , 108-20, (2013)

Glutamate transporters play important roles in the termination of excitatory neurotransmission and in providing cells throughout the body with glutamate for metabolic purposes. The high-affinity gluta...

A concise, asymmetric synthesis of (2R,3R)-3-hydroxyaspartic acid.

Amino Acids 35(2) , 507-10, (2008)

3-Hydroxyaspartic acid and its derivatives are found both in the free form and as peptide constituents in various microorganisms and fungi. Considering the biological importance of this amino acid and...

Insights into the mechanism of Pseudomonas dacunhae aspartate beta-decarboxylase from rapid-scanning stopped-flow kinetics.

Biochemistry 49 , 5066-73, (2010)

The mechanism of wild-type and R37A mutant Pseudomonas dacunhae aspartate beta-decarboxylase (ABDC) was studied by rapid-scanning stopped-flow spectrophotometry. Mixing wild-type ABDC with 50 mM disod...

DL-THREO-β-HYDROXYASPARTIC ACID

threo-2-Amino-3-hydroxysuccinic acid

DL-Threo-beta-Hydroxyaspartic Acid