1-((2r,4s,5r)-4-羟基-5-(羟基甲基)四氢呋喃-2-基)-2,4-二氧代-1,2,3,4-四氢嘧啶-5-甲醛

• 常用名: 1-((2r,4s,5r)-4-羟基-5-(羟基甲基)四氢呋喃-2-基)-2,4-二氧代-1,2,3,4-四氢嘧啶-5-甲醛
• 英文名: 5-Formyl-dU
• CAS号: 4494-26-2
• 分子量: 256.21200
• 密度: 1.67g/cm3
• 沸点: N/A
• 分子式: C₁₀H₁₂N₂O₆
• 熔点: N/A
• 闪点: N/A

名称

• 中文名: 1-((2R,4S,5R)-4-羟基-5-(羟基甲基)四氢呋喃-2-基)-2,4-二氧代-1,2,3,4-四氢嘧啶-5-甲醛
• 英文名: 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidine-5-carbaldehyde

物理化学性质

• 密度: 1.67g/cm3
• 分子式: C₁₀H₁₂N₂O₆
• 分子量: 256.21200
• 精确质量: 256.07000
• PSA: 121.62000
• InChIKey: MVORBLZUGBSUNB-XLPZGREQSA-N
• SMILES: O=Cc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=O
• 折射率: 1.676
• 储存条件: 2-8°C， 惰性气体

毒性和生态

安全信息

• 危害码 (欧洲): Xi

靶点实验

查看更多实验

实验名称：Cytotoxicity against HFF cell line by neutral red toxicity assay 来源：ChEMBL 靶标：HFF External Id：CHEMBL866302

实验名称：Antiviral activity against vaccinia virus Copenhagen measured as cytopathogenicity in... 来源：ChEMBL 靶标：Vaccinia virus External Id：CHEMBL867517

实验名称：Antiviral activity against vaccinia virus Copenhagen assessed as plaque reduction in ... 来源：ChEMBL 靶标：Vaccinia virus External Id：CHEMBL866299

实验名称：Antiviral activity against cowpox virus Brighton measured as cytopathogenicity in HFF... 来源：ChEMBL 靶标：Cowpox virus External Id：CHEMBL866300

实验名称：Antiviral activity against cowpox virus Brighton by plaque reduction in HFF cells 来源：ChEMBL 靶标：Cowpox virus External Id：CHEMBL866301

实验名称：Cytotoxicity against mouse L1210/0 cells after 48 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL918058

实验名称：Ratio of Vmax to that of dThd (Vmax = 0.14) 来源：ChEMBL 靶标：N/A External Id：CHEMBL852326

实验名称：Growth inhibition against HL-60 after 72 hours incubation period 来源：ChEMBL 靶标：HL-60 External Id：CHEMBL687513

实验名称：Michaelis-Menten constant (Km) against horse liver thymidine phosphorylase 来源：ChEMBL 靶标：Thymidine phosphorylase External Id：CHEMBL813689

实验名称：Antileishmanial activity against Leishmania donovani LV9 promastigotes by MTT method 来源：ChEMBL 靶标：Leishmania donovani External Id：CHEMBL871555

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英文别名

• 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
• 5-formyl-deoxyuridine
• 2'-deoxy-5-formyluridine
• 5-formyl-2'-deoxy-uridine
• Uridine,2'-deoxy-5-formyl
• 1-(4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
• 5-Formyl-dU