钙敏感受体拮抗剂I

• 常用名: 钙敏感受体拮抗剂I
• 英文名: Calcium-Sensing Receptor Antagonists I
• CAS号: 478963-79-0
• 分子量: 360.44900
• 密度: 1.085g/cm3
• 沸点: 510.1ºC at 760 mmHg
• 分子式: C₂₃H₂₄N₂O₂
• 熔点: N/A
• 闪点: 262.299ºC

钙敏感受体拮抗剂I用途

Calcium-Sensing Receptor Antagonists I是钙离子敏感的甲状旁腺素受体拮抗剂。

钙敏感受体拮抗剂I名称

• 中文名: 1-(1-甲基乙基)-4-[4-(1-甲基乙基)苯基]-6-(2-丙炔-1-基氧基)-2(1H)-喹唑啉酮
• 英文名: 1-propan-2-yl-4-(4-propan-2-ylphenyl)-6-prop-2-ynoxyquinazolin-2-one
• 中文别名: 1-(1-甲基乙基)-4-[4-(1-甲基乙基)苯基]-6-(2-丙炔-1-氧基)-2(1H)-喹唑啉

钙敏感受体拮抗剂I生物活性

• 描述: Calcium-Sensing Receptor Antagonists I是钙离子敏感的甲状旁腺素受体拮抗剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> CaSR的
  研究领域 >> 其他
• 参考文献:

  [1]. Widler, Leo et al. 1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: A Novel Series of Potent Calcium-Sensing Receptor Antagonists.Journal of Medicinal Chemistry(2010),53(5), 2250-2263.

钙敏感受体拮抗剂I物理化学性质

• 密度: 1.085g/cm3
• 沸点: 510.1ºC at 760 mmHg
• 分子式: C₂₃H₂₄N₂O₂
• 分子量: 360.44900
• 闪点: 262.299ºC
• 精确质量: 360.18400
• PSA: 44.12000
• LogP: 4.77980
• InChIKey: RXVZJHDMMKTKDR-UHFFFAOYSA-N
• SMILES: C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C
• 折射率: 1.572
• 储存条件: 2-8℃

钙敏感受体拮抗剂I靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A7681

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：qHTS assay to identify novel small-molecules to repurpose for Merkel cell carcinoma t... 来源：NCGC 靶标：N/A External Id：MCC011

实验名称：Primary qHTS for Identification of Calcium Integrin Binding Protein 1 (CIB1) Competit... 来源：NCGC External Id：CIB1-p1-p2

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钙敏感受体拮抗剂I英文别名

• CS-0307
• 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-2(1H)-QUINAZOLINONE
• Calcium-Sensing Receptor Antagonists I