银杏双黄酮

• 常用名: 银杏双黄酮
• 英文名: ginkgetin
• CAS号: 481-46-9
• 分子量: 566.511
• 密度: 1.5±0.1 g/cm3
• 沸点: 863.7±65.0 °C at 760 mmHg
• 分子式: C₃₂H₂₂O₁₀
• 熔点: 336ºC
• 闪点: 287.2±27.8 °C

银杏双黄酮用途

银杏双黄酮(Ginkgetin)是一种天然的双类黄酮，从银杏叶中分离，抗炎和抗癌生物活性。

银杏双黄酮名称

• 中文名: 银杏素
• 英文名: ginkgetin
• 中文别名: 银杏双黄酮 | 白果双黄酮

银杏双黄酮生物活性

• 描述: 银杏双黄酮(Ginkgetin)是一种天然的双类黄酮,从银杏叶中分离,抗炎和抗癌生物活性。
• 相关类别:
  信号通路 >> 其他 >> 其他
  天然产物 >> 黄酮类化合物
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Son JK, et al. Ginkgetin, a Biflavone from Ginko biloba leaves, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. Biol Pharm Bull. 2005 Dec;28(12):2181-4.

  [2]. Jeon YJ, et al. Ginkgetin inhibits the growth of DU-145 prostate cancer cells through inhibition of STAT3 activity. Cancer Sci. 2015 Jan 22. doi: 10.1111/cas.12608.

  [3]. You OH, et al. Ginkgetin induces apoptosis via activation of caspase and inhibition of survival genes in PC-3 prostate cancer cells. Bioorg Med Chem Lett. 2013 May 1;23(9):2692-5.

  [4]. Kwak WJ, et al. Effects of Ginkgetin from Ginkgo biloba Leaves on cyclooxygenases and in vivo skin inflammation. Planta Med. 2002 Apr;68(4):316-21.

银杏双黄酮物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 863.7±65.0 °C at 760 mmHg
• 熔点: 336ºC
• 分子式: C₃₂H₂₂O₁₀
• 分子量: 566.511
• 闪点: 287.2±27.8 °C
• 精确质量: 566.121277
• PSA: 159.80000
• LogP: 4.45
• InChIKey: AIFCFBUSLAEIBR-UHFFFAOYSA-N
• SMILES: COc1cc(O)c2c(=O)cc(-c3ccc(OC)c(-c4c(O)cc(O)c5c(=O)cc(-c6ccc(O)cc6)oc45)c3)oc2c1
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.714
• 储存条件: -20°C

银杏双黄酮靶点实验

查看更多实验

实验名称：Cytotoxicity against human NCI-H187 cells at 10 ug/mL 来源：ChEMBL 靶标：NCI-H187 External Id：CHEMBL928073

实验名称：Potentiation of 5-FU-induced cytotoxicity in human HCT-116 cells assessed as reductio... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5236489

实验名称：Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability at 1... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5236488

实验名称：Downregulation of MDM2 protein expression in human HCT-116 cells at 10 uM incubated f... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5236491

实验名称：Cytotoxicity against human breast cancer cells at 10 ug/mL 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL933624

实验名称：Upregulation of p53 protein expression in human HCT-116 cells at 10 uM incubated for ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5236490

实验名称：Induction of ferroptosis in human HCT-116 cells assessed as reduction in GSH content ... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5236485

实验名称：Induction of ferroptosis in human HCT-116 cells assessed as increase in iron content ... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5236484

实验名称：Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability at 1... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5236487

实验名称：Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability at 1... 来源：ChEMBL 靶标：HCT-116 External Id：CHEMBL5236486

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银杏双黄酮英文别名

• 7,4'-di-O-methylamentoflavone
• Amentoflavone 7,4'-dimethyl ether
• 5,7-Dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-chromen-4-one
• ginkgetin
• 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one