麦角硫因

• 常用名: 麦角硫因
• 英文名: L-(+)-Ergothioneine
• CAS号: 497-30-3
• 分子量: 229.299
• 密度: N/A
• 沸点: N/A
• 分子式: C₉H₁₅N₃O₂S
• 熔点: 275-277ºC (dec.)
• 闪点: N/A

麦角硫因用途

Ergothioneine 是组氨酸甜菜碱的咪唑-2-硫酮衍生物,是由某些细菌和真菌合成的。Ergothioneine 通常被认为是抗氧化剂。

麦角硫因名称

• 中文名: 麦角硫因
• 英文名: ergothioneine
• 中文别名: 2-巯基组氨酸甜菜碱

麦角硫因生物活性

• 描述: Ergothioneine 是组氨酸甜菜碱的咪唑-2-硫酮衍生物,是由某些细菌和真菌合成的。Ergothioneine 通常被认为是抗氧化剂。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Oumari M, et al. Regeneration of ergothioneine after reaction with singlet oxygen. Free Radic Biol Med. 2019 Apr;134:498-504.

麦角硫因物理化学性质

• 熔点: 275-277ºC (dec.)
• 分子式: C₉H₁₅N₃O₂S
• 分子量: 229.299
• 精确质量: 229.088501
• PSA: 100.97000
• LogP: -3.43
• InChIKey: SSISHJJTAXXQAX-ZETCQYMHSA-N
• SMILES: C[N+](C)(C)C(Cc1c[nH]c(=S)[nH]1)C(=O)[O-]
• 外观性状: 白色固体
• 储存条件: -20°C

麦角硫因安全信息

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3

麦角硫因靶点实验

查看更多实验

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Enzymatic assay of human HDAC6 with custom peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808150

实验名称：Chemical Probes of Kaposi's Sarcoma Herpes Virus Latent Infection 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：ORF 73 [Human herpesvirus 8 type M] External Id：HMS791

实验名称：Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1315

实验名称：High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS1303

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H... 来源：Southern Research Institute 靶标：CFTR External Id：CF Folding

实验名称：MELAS cybrid survival enhancement under low glucose conditions 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1419

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麦角硫因英文别名

• ergothioneine
• L-Ergothioneine
• (2S)-3-(2-Thioxo-2,3-dihydro-1H-imidazol-4-yl)-2-(trimethylammonio)propanoate
• [(S)-1-carboxy-2-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-ethyl]-trimethyl-ammonium,betaine
• Thiolhistidine betaine
• Sympectothion
• (S)-a-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium Hydroxide Inner Salt
• L(+)-Ergothioneine
• Thiotane
• 2-thiol-L-histidine-betaine
• [(S)-1-Carboxy-2-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-aethyl]-trimethyl-ammonium,Betain
• Ammonium, [1-carboxy-2-(2-thioxo-4-imidazolin-4-yl)ethyl]trimethyl-, hydroxide, inner salt
• (2S)-3-(2-Sulfanyl-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate
• [1-Carboxy-2-[2-mercaptoimidazol-4(or 5)-yl]ethyl]trimethylammonium Hydroxide Inner Salt
• thiotaine
• Thiasine
• Thiolhistidine-βine
• Phytothioneine