L-(+)-Ergothioneine

Modify Date: 2025-08-22 14:55:55

L-(+)-Ergothioneine Structure
L-(+)-Ergothioneine structure
Common Name L-(+)-Ergothioneine
CAS Number 497-30-3 Molecular Weight 229.299
Density N/A Boiling Point N/A
Molecular Formula C9H15N3O2S Melting Point 275-277ºC (dec.)
MSDS USA Flash Point N/A

 Use of L-(+)-Ergothioneine


Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant[1].

 Names

Name ergothioneine
Synonym More Synonyms

 L-(+)-Ergothioneine Biological Activity

Description Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant[1].
Related Catalog
References

[1]. Oumari M, et al. Regeneration of ergothioneine after reaction with singlet oxygen. Free Radic Biol Med. 2019 Apr;134:498-504.

 Chemical & Physical Properties

Melting Point 275-277ºC (dec.)
Molecular Formula C9H15N3O2S
Molecular Weight 229.299
Exact Mass 229.088501
PSA 100.97000
LogP -3.43
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles43

More Articles
Effect of mushroom diet on pharmacokinetics of gabapentin in healthy Chinese subjects.

Br. J. Clin. Pharmacol. 78(1) , 129-34, (2014)

This study evaluated the pharmacokinetics of gabapentin in Chinese subjects who received a diet rich in shiitake mushrooms. Shiitake mushrooms have been shown to contain high amount of ergothioneine. ...

The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis.

Eukaryotic Cell 11(10) , 1226-38, (2012)

The function of a number of genes in the gliotoxin biosynthetic cluster (gli) in Aspergillus fumigatus remains unknown. Here, we demonstrate that gliK deletion from two strains of A. fumigatus complet...

Uptake and protective effects of ergothioneine in human endothelial cells.

J. Pharmacol. Exp. Ther. 350(3) , 691-700, (2014)

Ergothioneine is a thiourea derivative of histidine found in food, especially mushrooms. Experiments in cell-free systems and chemical assays identified this compound as a powerful antioxidant. Experi...

 Synonyms

ergothioneine
L-Ergothioneine
(2S)-3-(2-Thioxo-2,3-dihydro-1H-imidazol-4-yl)-2-(trimethylammonio)propanoate
[(S)-1-carboxy-2-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-ethyl]-trimethyl-ammonium,betaine
Thiolhistidine betaine
Sympectothion
(S)-a-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium Hydroxide Inner Salt
L(+)-Ergothioneine
Thiotane
2-thiol-L-histidine-betaine
1H-Imidazole-4-ethanaminium, α-carboxy-2-mercapto-N,N,N-trimethyl-, inner salt, (αS)-
[(S)-1-Carboxy-2-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)-aethyl]-trimethyl-ammonium,Betain
Ammonium, [1-carboxy-2-(2-thioxo-4-imidazolin-4-yl)ethyl]trimethyl-, hydroxide, inner salt
(2S)-3-(2-Sulfanyl-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate
[1-Carboxy-2-[2-mercaptoimidazol-4(or 5)-yl]ethyl]trimethylammonium Hydroxide Inner Salt
thiotaine
Thiasine
1H-imidazole-5-ethanaminium, α-carboxy-2-mercapto-N,N,N-trimethyl-, inner salt, (αS)-
Thiolhistidine-βine
Phytothioneine
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