SAR502250

• 常用名: SAR502250
• 英文名: SAR502250
• CAS号: 503860-57-9
• 分子量: 367.37700
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₈FN₅O₂
• 熔点: N/A
• 闪点: N/A

SAR502250用途

SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimer’s disease (AD).

SAR502250名称

• 英文名: uda-680

SAR502250物理化学性质

• 分子式: C₁₉H₁₈FN₅O₂
• 分子量: 367.37700
• 精确质量: 367.14400
• PSA: 73.14000
• LogP: 2.01930
• InChIKey: NKUNFNVAHJNALA-QGZVFWFLSA-N
• SMILES: Cn1c(N2CCOC(c3ccc(F)cc3)C2)nc(-c2ccncn2)cc1=O

SAR502250英文别名

• 2-[(2S)-2-(2-(4-fluorophenyl)morpholin-4-yl)]-1-methyl-1H-[4,4']bipyrimidinyl-6-one