n-丁基-(9ci)-1H-苯并咪唑-2-胺

• 常用名: n-丁基-(9ci)-1H-苯并咪唑-2-胺
• 英文名: 1H-Benzimidazol-2-amine,N-butyl
• CAS号: 51314-51-3
• 分子量: 189.26
• 密度: 1.153g/cm3
• 沸点: 344.8ºC at 760 mmHg
• 分子式: C₁₁H₁₅N₃
• 熔点: N/A
• 闪点: 162.3ºC

n-丁基-(9ci)-1H-苯并咪唑-2-胺用途

M084,一种苯并咪唑衍生物,可抑制线粒体呼吸,激活线粒体未折叠蛋白反应和 AMPK,招募 SIR-2.1 和 SKN-1,最终通过转录因子 DAF-16,延缓线虫的衰老过程。

n-丁基-(9ci)-1H-苯并咪唑-2-胺名称

• 中文名: n-丁基-(9ci)-1H-苯并咪唑-2-胺
• 英文名: butyl(1,3-dihydrobenzimidazol-2-ylidene)azanium

n-丁基-(9ci)-1H-苯并咪唑-2-胺生物活性

• 描述: M084,一种苯并咪唑衍生物,可抑制线粒体呼吸,激活线粒体未折叠蛋白反应和 AMPK,招募 SIR-2.1 和 SKN-1,最终通过转录因子 DAF-16,延缓线虫的衰老过程。
• 相关类别:
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Ai-Jun Ding, et al. Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way. Mol Cell Biochem. 2017 Feb;426(1-2):101-109.

n-丁基-(9ci)-1H-苯并咪唑-2-胺物理化学性质

• 密度: 1.153g/cm3
• 沸点: 344.8ºC at 760 mmHg
• 分子式: C₁₁H₁₅N₃
• 分子量: 189.26
• 闪点: 162.3ºC
• 精确质量: 189.12700
• PSA: 40.71000
• LogP: 2.84790
• InChIKey: OKKUCNXCFWODOE-UHFFFAOYSA-N
• SMILES: CCCCNc1nc2ccccc2[nH]1
• 折射率: 1.653

n-丁基-(9ci)-1H-苯并咪唑-2-胺安全信息

• 海关编码: 2933990090

n-丁基-(9ci)-1H-苯并咪唑-2-胺海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

n-丁基-(9ci)-1H-苯并咪唑-2-胺靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Specificity screen against TRPC6 for compounds that activate transient receptor poten... 来源：Johns Hopkins Ion Channel Center 靶标：short transient receptor potential channel 6 [Mus musculus] External Id：TRPC4_AG_Counter_C6

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Specificity screen against TRPC6 for compounds that inhibit transient receptor potent... 来源：Johns Hopkins Ion Channel Center 靶标：short transient receptor potential channel 6 [Mus musculus] External Id：TRPC4_Inh_Counter_C6

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

共132条，当前第1页，共14页

1

2

3

4

5

n-丁基-(9ci)-1H-苯并咪唑-2-胺英文别名

• 2-N-butylamino-1H-benzimidazole
• 2-n-Butylaminobenzimidazol
• N-Butyl-1H-Benzimidazol-2-Amine