7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one

• 常用名: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
• 英文名: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
• CAS号: 52391-89-6
• 分子量: 318.73000
• 密度: 1.4g/cm3
• 沸点: 550.3ºC at 760mmHg
• 分子式: C₁₆H₁₂ClFN₂O₂
• 熔点: N/A
• 闪点: 286.6ºC

名称

• 英文名: 7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one

物理化学性质

• 密度: 1.4g/cm3
• 沸点: 550.3ºC at 760mmHg
• 分子式: C₁₆H₁₂ClFN₂O₂
• 分子量: 318.73000
• 闪点: 286.6ºC
• 精确质量: 318.05700
• PSA: 52.90000
• LogP: 2.11190
• InChIKey: RMFYWNFETXNTIQ-UHFFFAOYSA-N
• SMILES: CN1C(=O)C(O)N=C(c2ccccc2F)c2cc(Cl)ccc21
• 折射率: 1.641

毒性和生态

靶点实验

查看更多实验

实验名称：ED50 value was reported as log1/C, which is the concentration required to reduce loco... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL797716

实验名称：Halving of lever pressing in non punished rats, ED50 value reported as log 1/C 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL797719

实验名称：Fourfod increase in lever pressing in punished rats, ED50 value reported as log1/C 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL797717

实验名称：Partition coefficient (logP) 来源：ChEMBL 靶标：N/A External Id：CHEMBL632465

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英文别名

• FLUTEMAZEPAM
• Flutemazepam [INN]
• Flutemazepamum [Latin]
• EINECS 257-892-1
• 7-Chloro-1,3-dihydro-1-methyl-3-hydroxy-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one
• Sas-646
• 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
• 2H-1,4-Benzodiazepin-2-one,1,3-dihydro-7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-methyl