氯泼尼醇

• 常用名: 氯泼尼醇
• 英文名: cloprednol
• CAS号: 5251-34-3
• 分子量: 392.87300
• 密度: 1.4g/cm3
• 沸点: 600.3ºC at 760mmHg
• 分子式: C₂₁H₂₅ClO₅
• 熔点: N/A
• 闪点: 316.9ºC

氯泼尼醇用途

Cloprednol 是一种具有口服活性的合成糖皮质激素。Cloprednol 具有抗炎活性,可用于哮喘研究。

氯泼尼醇名称

• 中文名: 氯泼尼醇
• 英文名: (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one

氯泼尼醇生物活性

• 描述: Cloprednol 是一种具有口服活性的合成糖皮质激素。Cloprednol 具有抗炎活性,可用于哮喘研究。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Gavani UD, et al. Long-term cloprednol use in chronic asthma. JAMA. 1979 Dec 14;242(24):2679-82.

氯泼尼醇物理化学性质

• 密度: 1.4g/cm3
• 沸点: 600.3ºC at 760mmHg
• 分子式: C₂₁H₂₅ClO₅
• 分子量: 392.87300
• 闪点: 316.9ºC
• 精确质量: 392.13900
• PSA: 94.83000
• LogP: 1.90010
• InChIKey: YTJIBEDMAQUYSZ-FDNPDPBUSA-N
• SMILES: CC12C=CC(=O)C=C1C(Cl)=CC1C2C(O)CC2(C)C1CCC2(O)C(=O)CO
• 折射率: 1.635

氯泼尼醇靶点实验

查看更多实验

实验名称：Compound was evaluated for inhibition of rat Gabra1 in an in vitro assay with cellula... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291801

实验名称：Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291798

实验名称：Antagonist activity at human GABRA1 in an in vitro cell-based assay measured by fluor... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit gamma-2 External Id：CHEMBL5291797

实验名称：Binding affinity towards human ESR1 in an in vitro cell free assay (NIBR assay) measu... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL5291791

实验名称：Binding affinity towards human HRH3 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Histamine H3 receptor External Id：CHEMBL5291921

实验名称：Binding affinity towards human EDNRA in an in vitro assay with cellular components me... 来源：ChEMBL 靶标：Endothelin-1 receptor External Id：CHEMBL5291785

实验名称：Binding affinity towards human DRD2 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：D(2) dopamine receptor External Id：CHEMBL5291781

实验名称：Agonist activity at human DRD1 in an in vitro cell-based assay measured by time-resol... 来源：ChEMBL 靶标：D(1A) dopamine receptor External Id：CHEMBL5291777

实验名称：Antagonist activity at human CNR1 in an in vitro cell-based assay measured by fluores... 来源：ChEMBL 靶标：Cannabinoid receptor 1 External Id：CHEMBL5291772

实验名称：Binding affinity towards human DRD3 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：D(3) dopamine receptor External Id：CHEMBL5291899

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氯泼尼醇英文别名

• CLOPREDNOL
• Cloradryn
• Cloprednole
• Syntestan
• Novacort
• Cloprednolum
• Synestan
• RS 4691