L2-b

• 常用名: L2-b
• 英文名: L2-b
• CAS号: 52688-60-5
• 分子量: 227.30500
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₁₇N₃
• 熔点: N/A
• 闪点: N/A
• 符号: GHS07
• 信号词: Warning

L2-b用途

L2-b is a bifunctional Aβ-interacting, metal-chelating molecule that modulates ROS production in, and improves survival of neuroblastoma cells incubated in the presence of Aβ along with Copper or Zinc. In cell-free aggregation studies, L2-b inhibits metal-induced Aβ aggregation, and also promotes the dissociation of Ab aggregates in homogenates of human AD brain samples.

L2-b名称

• 英文名: N1,N1-dimethyl-N4-(pyridin-2-ylmethyl)benzene-1,4-diamine

L2-b物理化学性质

• 分子式: C₁₄H₁₇N₃
• 分子量: 227.30500
• 精确质量: 227.14200
• PSA: 28.16000
• LogP: 2.83270

L2-b安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 危险品运输编码: NONH for all modes of transport

L2-b靶点实验

查看更多实验

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

实验名称：Reversible inhibition of human recombinant MAOB using kynuramine as substrate at 2 ti... 来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B External Id：CHEMBL3225597

实验名称：HTS to identify compounds that affect the blood-brain barrier permeability in vitro 来源：26908 靶标：N/A External Id：HTS97080

实验名称：Selectivity index, ratio of Ki for human recombinant MAOA to Ki for human recombinant... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3225596

实验名称：Inhibitors of CDC25B-CDK2/CyclinA interaction 来源：Center for Chemical Genomics, University of Michigan External Id：MScreen:TargetID_600

实验名称：Competitive inhibition of human recombinant MAOB using kynuramine as substrate after ... 来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B External Id：CHEMBL3225598

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