[3-(4-氯苯基)-1-苯基-1H-吡唑-4-基]乙酸

• 常用名: [3-(4-氯苯基)-1-苯基-1H-吡唑-4-基]乙酸
• 英文名: 1H-Pyrazole-4-aceticacid, 3-(4-chlorophenyl)-1-phenyl
• CAS号: 53808-88-1
• 分子量: 312.75000
• 密度: 1.3g/cm3
• 沸点: 525.1ºC at 760mmHg
• 分子式: C₁₇H₁₃ClN₂O₂
• 熔点: N/A
• 闪点: 271.4ºC

[3-(4-氯苯基)-1-苯基-1H-吡唑-4-基]乙酸用途

Lonazolac是一种非甾体抗风湿药物。抗炎作用[1]。

[3-(4-氯苯基)-1-苯基-1H-吡唑-4-基]乙酸名称

• 中文名: 氯那唑酸
• 英文名: lonazolac

[3-(4-氯苯基)-1-苯基-1H-吡唑-4-基]乙酸生物活性

• 描述: Lonazolac是一种非甾体抗风湿药物。抗炎作用[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Trnavský K, et al. [Lonazolac - a new non-steroidal antirheumatic agent. Report of a double-blind crossover clinical study]. Fysiatr Revmatol Vestn. 1983;61(3):147-152.

  [2]. Harras MF, et al. Discovery of new non-acidic lonazolac analogues with COX-2 selectivity as potent anti-inflammatory agents. Medchemcomm. 2019;10(10):1775-1788. Published 2019 Jul 22.

[3-(4-氯苯基)-1-苯基-1H-吡唑-4-基]乙酸物理化学性质

• 密度: 1.3g/cm3
• 沸点: 525.1ºC at 760mmHg
• 分子式: C₁₇H₁₃ClN₂O₂
• 分子量: 312.75000
• 闪点: 271.4ºC
• 精确质量: 312.06700
• PSA: 55.12000
• LogP: 3.81980
• InChIKey: XVUQHFRQHBLHQD-UHFFFAOYSA-N
• SMILES: O=C(O)Cc1cn(-c2ccccc2)nc1-c1ccc(Cl)cc1

[3-(4-氯苯基)-1-苯基-1H-吡唑-4-基]乙酸靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity 来源：NCGC External Id：HERG01

实验名称：qHTS for Inhibitors of TGF-b: Cytotox Counterscreen 来源：NCGC 靶标：N/A External Id：SMAD3201

实验名称：uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay 来源：Burnham Center for Chemical Genomics 靶标：cystic fibrosis transmembrane conductance regulator [Homo sapiens] External Id：SBCCG-A764-CF-PAF-Primary-Assay

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ant... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_ANT_FLUO8_1536_1X%INH PRUN

实验名称：qHTS for Inhibitors of TGF-b 来源：NCGC 靶标：Smad3 [Homo sapiens] External Id：SMAD3101

实验名称：qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green ... 来源：NCGC 靶标：N/A External Id：Ebola screen2_EMI141217_green

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[3-(4-氯苯基)-1-苯基-1H-吡唑-4-基]乙酸英文别名

• 2-[3-(4-chlorophenyl)-1-phenylpyrazol-4-yl]acetic acid
• Lonazolacum
• Irritren
• Lonazolaco
• Lonazolac